Evidence map›Paper›PMID 35614045›Full record

ArticleNature communications2022

Serotonin limits generation of chromaffin cells during adrenal organ development.

Polina Kameneva, Victoria I Melnikova, Maria Eleni Kastriti, Anastasia Kurtova, Emil Kryukov, Aliia Murtazina, Louis Faure, Irina Poverennaya, Artem V Artemov, Tatiana S Kalinina and 18 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Special Issue "Serotonin in Health and Diseases".International journal of molecular sciences · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Science advances · 2024
    Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. What made us "hunter-gatherers of words".Frontiers in neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 10 institutions in 7 countries.

Polina Kameneva *Department of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Victoria I Melnikova *Koltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0003-2851-7039
Maria Eleni KastritiDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.ORCID 0000-0002-0563-7399
Anastasia KurtovaKoltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0002-9713-7008
Emil KryukovDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.ORCID 0000-0001-8506-0448
Aliia MurtazinaDepartment of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden.
Louis FaureDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.ORCID 0000-0003-4621-586X
Irina PoverennayaDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Artem V ArtemovDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria.
Tatiana S KalininaFederal state budgetary institution "Research Zakusov Institute of Pharmacology" (FSBI "Zakusov Institute of Pharmacology"), Russian Academy of Sciences, Moscow, Russia.
Nikita V KudryashovFederal state budgetary institution "Research Zakusov Institute of Pharmacology" (FSBI "Zakusov Institute of Pharmacology"), Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0002-1819-1867
Michael BaderMax-Delbrück Center for Molecular Medicine (MDC), 13125, Berlin-Buch, Germany.
Jan SkodaDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.ORCID 0000-0002-9292-8177
Petr ChlapekDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.
Lucie CurylovaDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.ORCID 0000-0001-7067-4383
Lukas SouradaDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.ORCID 0000-0002-2219-7575
Jakub NeradilDepartment of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.ORCID 0000-0001-6781-7099
Marketa TesarovaCentral European Institute of Technology, Brno University of Technology, Brno, Czech Republic.ORCID 0000-0002-5200-7365
Massimo PasqualettiUnit of Cell and Developmental Biology, Department of Biology, University of Pisa, Pisa, Italy.ORCID 0000-0002-0844-8139
Patricia GasparINSERM, Paris Brain Institute, Paris, France.ORCID 0000-0003-4217-5717
Vasily D YakushovSevertsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, Russia.
Boris I SheftelSevertsov Institute of Ecology and Evolution, Russian Academy of Sciences, Moscow, Russia.
Tomas ZikmundCentral European Institute of Technology, Brno University of Technology, Brno, Czech Republic.ORCID 0000-0003-2948-5198
Jozef KaiserCentral European Institute of Technology, Brno University of Technology, Brno, Czech Republic.ORCID 0000-0002-7397-125X
Kaj FriedDepartment of Neuroscience, Karolinska Institute, Stockholm, Sweden.
Natalia AleninaMax-Delbrück Center for Molecular Medicine (MDC), 13125, Berlin-Buch, Germany.
Elena E VoronezhskayaKoltsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia. elena.voronezhskaya@idbras.ru.
Igor AdameykoDepartment of Neuroimmunology, Center for Brain Research, Medical University Vienna, Vienna, Austria. igor.adameyko@ki.se.ORCID 0000-0001-5471-0356
Karolinska Institutet · SEMasaryk University · CZCentral European Institute of Technology · CZKoltzov Institute of Developmental Biology · RUMedical University of Vienna · ATMax Delbrück Center · DERussian Academy of Sciences · RUSevertsov Institute of Ecology and Evolution · RUInserm · FRUniversity of Pisa · IT

Funding

Austrian Science Fund FWF DOC 33
6 · The paper itself

Abstract

Adrenal glands are the major organs releasing catecholamines and regulating our stress response. The mechanisms balancing generation of adrenergic chromaffin cells and protecting against neuroblastoma tumors are still enigmatic. Here we revealed that serotonin (5HT) controls the numbers of chromaffin cells by acting upon their immediate progenitor "bridge" cells via 5-hydroxytryptamine receptor 3A (HTR3A), and the aggressive HTR3A

Indexed as

Chromaffin CellsNeuroblastomaAdrenal GlandsAnimalsCatecholaminesFemaleMicePregnancySerotoninCatecholaminesSerotonin

Identifiers

PMID35614045
PMCPMC9133002
OpenAlexW4281491826

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.