Evidence map›Paper›PMID 35613942›Full record

ArticleMethods of information in medicine2022

A Systematic Approach to Configuring MetaMap for Optimal Performance.

Xia Jing, Akash Indani, Nina Hubig, Hua Min, Yang Gong, James J Cimino, Dean F Sittig, Lior Rennert, David Robinson, Paul Biondich and 5 more

Abstract read
In one paragraph

Article in Methods of information in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Active Learning Pipeline to Identify Candidate Terms for a CDSS Ontology.Studies in health technology and informatics · 2024
    Article
  4. Knowledge Engineering for Medical Vocabularies Using Large Language Models.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xia JingDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, South Carolina, United States.
Akash IndaniSchool of Computing, College of Engineering, Computing and Applied Sciences, Clemson University, Clemson, South Carolina, United States.
Nina HubigSchool of Computing, College of Engineering, Computing and Applied Sciences, Clemson University, Clemson, South Carolina, United States.
Hua MinDepartment of Health Administration and Policy, College of Health and Human Services, George Mason University, Fairfax, Virginia, United States.
Yang GongSchool of Biomedical Informatics, The University of Texas Health Sciences Center at Houston, Houston, Texas, United States.
James J CiminoInformatics Institute, The University of Alabama at Birmingham, Birmingham, Alabama, United States.
Dean F SittigSchool of Biomedical Informatics, The University of Texas Health Sciences Center at Houston, Houston, Texas, United States.
Lior RennertDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, South Carolina, United States.
David RobinsonIndependent Consultant, Cumbria, United kingdom.
Paul BiondichDepartment of Pediatrics, Clem McDonald Biomedical Informatics Center, Regenstrief Institute, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Adam WrightDepartment of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, United States.
Christian NøhrDepartment of Planning, Faculty of Engineering, Aalborg University, Aalborg, Denmark.
Timothy LawOhio Musculoskeletal and Neurologic Institute, Ohio University, Athens, Ohio, United States.
Arild FaxvaagDepartment of Neuromedicine and Movement Science, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Ronald GimbelDepartment of Public Health Sciences, College of Behavioral, Social and Health Sciences, Clemson University, Clemson, South Carolina, United States.

Funding

Tissue Structural and Neural Remodeling in Human Sacroiliac JointP20GM121342 · NIGMS · CLEMSON UNIVERSITY · PI Hai Yao · 2018 to 2026
$24.7M
Open, interoperable, and configurable clinical decision support modules for OpenMRS, OpenEMR, and beyondR01GM138589 · NIGMS · CLEMSON UNIVERSITY · PI JING, XIA · 2020 to 2024
$1.9M
NIGMS NIH HHS P20 GM121342NIGMS NIH HHS R01 GM138589
6 · The paper itself

Abstract

backgroundMetaMap is a valuable tool for processing biomedical texts to identify concepts. Although MetaMap is highly configurative, configuration decisions are not straightforward.

objectiveTo develop a systematic, data-driven methodology for configuring MetaMap for optimal performance.

methodsMetaMap, the word2vec model, and the phrase model were used to build a pipeline. For unsupervised training, the phrase and word2vec models used abstracts related to clinical decision support as input. During testing, MetaMap was configured with the default option, one behavior option, and two behavior options. For each configuration, cosine and soft cosine similarity scores between identified entities and gold-standard terms were computed for 40 annotated abstracts (422 sentences). The similarity scores were used to calculate and compare the overall percentages of exact matches, similar matches, and missing gold-standard terms among the abstracts for each configuration. The results were manually spot-checked. The precision, recall, and F-measure (

resultsThe percentages of exact matches and missing gold-standard terms were 0.6-0.79 and 0.09-0.3 for one behavior option, and 0.56-0.8 and 0.09-0.3 for two behavior options, respectively. The percentages of exact matches and missing terms for soft cosine similarity scores exceeded those for cosine similarity scores. The average precision, recall, and F-measure were 0.59, 0.82, and 0.68 for exact matches, and 1.00, 0.53, and 0.69 for missing terms, respectively.

conclusionWe demonstrated a systematic approach that provides objective and accurate evidence guiding MetaMap configurations for optimizing performance. Combining objective evidence and the current practice of using principles, experience, and intuitions outperforms a single strategy in MetaMap configurations. Our methodology, reference codes, measurements, results, and workflow are valuable references for optimizing and configuring MetaMap.

Identifiers

PMID35613942
PMCPMC9788913

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.