Evidence map›Paper›PMID 35613840›Full record

ReviewJournal of neurointerventional surgery2023

Machine learning and acute stroke imaging.

Sunil A Sheth, Luca Giancardo, Marco Colasurdo, Visish M Srinivasan, Arash Niktabe, Peter Kan

Registry-linked trialAbstract readReview
In one paragraph

Review in Journal of neurointerventional surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06018545 (AI Assisted Reader Evaluation in Acute CT Head Interpretation), which is not on this map. Cited by 37 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06018545 completednot on this map

AI Assisted Reader Evaluation in Acute CT Head Interpretation

TypeobservationalSponsorOxford University Hospitals NHS TrustRan2023 to 2025Enrolled33ConditionsIntracranial Hemorrhages, Acute Ischemic Stroke, Hydrocephalus, Cerebral InfarctionArmsGround truthing, Reading
3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Predictive analysis in acute ischemic stroke imaging.Annals of medicine and surgery (2012) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Current state and advancements of imaging in acute ischemic stroke: a practical review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  13. An artificial intelligence (AI)-based approach to clinical trial recruitment: The impact of Viz RECRUIT on enrollment in the EMBOLISE trial.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  14. Article
  15. Article
  16. Cerebrovascular morphology: Insights into normal variations, aging effects and disease implications.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sunil A ShethDepartment of Neurology, UTHealth McGovern Medical School, Houston, Texas, USA Sunil.A.Sheth@uth.tmc.edu.
Luca GiancardoCenter for Precision Health, School of Biomedical Informatics, University of Texas Health Science Center at Houston, Houston, Texas, USA.
Marco ColasurdoDepartment of Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA.
Visish M SrinivasanDepartment of Neurosurgery, Barrow Neurological Institute, Phoenix, Arizona, USA.
Arash NiktabeDepartment of Neurology, UTHealth McGovern Medical School, Houston, Texas, USA.
Peter KanDepartment of Neurosurgery, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA.ORCID http://orcid.org/0000-0001-6649-4128

Funding

Deep Learning Enabled Endovascular Stroke Therapy Screening in Community HospitalsR01NS121154 · NINDS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI GIANCARDO, LUCA, SHETH, SUNIL · 2021 to 2025
$2.2M
NINDS NIH HHS R01 NS121154
6 · The paper itself

Abstract

backgroundIn recent years, machine learning (ML) has had notable success in providing automated analyses of neuroimaging studies, and its role is likely to increase in the future. Thus, it is paramount for clinicians to understand these approaches, gain facility with interpreting ML results, and learn how to assess algorithm performance.

objectiveTo provide an overview of ML, present its role in acute stroke imaging, discuss methods to evaluate algorithms, and then provide an assessment of existing approaches.

methodsIn this review, we give an overview of ML techniques commonly used in medical imaging analysis and methods to evaluate performance. We then review the literature for relevant publications. Searches were run in November 2021 in Ovid Medline and PubMed. Inclusion criteria included studies in English reporting use of artificial intelligence (AI), machine learning, or similar techniques in the setting of, and in applications for, acute ischemic stroke or mechanical thrombectomy. Articles that included image-level data with meaningful results and sound ML approaches were included in this discussion.

resultsMany publications on acute stroke imaging, including detection of large vessel occlusion, detection and quantification of intracranial hemorrhage and detection of infarct core, have been published using ML methods. Imaging inputs have included non-contrast head CT, CT angiograph and MRI, with a range of performances. We discuss and review several of the most relevant publications.

conclusionsML in acute ischemic stroke imaging has already made tremendous headway. Additional applications and further integration with clinical care is inevitable. Thus, facility with these approaches is critical for the neurointerventional clinician.

Indexed as

Ischemic StrokeStrokeArtificial IntelligenceHumansMachine LearningMagnetic Resonance ImagingInterventionStroke

Identifiers

PMID35613840
PMCPMC10523646

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.