Evidence map›Paper›PMID 35613828›Full record

SynthesisOpen heart2022

Thromboembolic events in left ventricular non-compaction: comparison between children and adults - a systematic review and meta-analysis.

Keiichi Hirono, Shinya Takarada, Nariaki Miyao, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Hideki Origasa, Fukiko Ichida

Open access · goldAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  9. [Cardiac MRI in nonischemic cardiomyopathies].Radiologie (Heidelberg, Germany) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Keiichi HironoDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan khirono1973@gmail.com.ORCID 0000-0002-4224-9053
Shinya TakaradaDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.
Nariaki MiyaoDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.
Hideyuki NakaokaDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.ORCID 0000-0002-4113-5900
Keijiro IbukiDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.
Sayaka OzawaDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.
Hideki OrigasaDepartment of Pediatrics and Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.
Fukiko IchidaDepartment of Pediatrics, International University of Health and Welfare, Otawara, Japan.
University of Toyama · JPInternational University of Health and Welfare · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveLeft ventricular non-compaction (LVNC) is morphologically characterised by excessive trabeculations and deep recesses in the ventricular wall. The risk of thromboembolic disease in the paediatric patients with LVNC has not been clearly established. We conducted this systematic review to evaluate the prevalence and incidence of thromboembolism (TE) in paediatric and adult patients with LVNC and searched for risk factors for TE to explore management strategies.

methodsThe primary outcome was the prevalence and incidence of TE in the patients with LVNC. The secondary outcome was the TE and mortality and heart transplantation rates between paediatric and adult patients with LVNC. We searched for studies published in MEDLINE, Embase and Cochrane Central Register of Controlled Trials between January 1950 and December 2020. A systematic search of keywords related to LVNC, anticoagulants/antiplatelets and TE was conducted. Studies that did not present original research, non-human studies, duplicated studies were excluded.

resultsFifty-seven studies met the inclusion criteria. A total of 726 paediatric and 3862 adult patients were included. The mean prevalence rates of TE in the paediatric and adult patients with LVNC were 2.6% and 6.2% (I

conclusionsThe prevalence and incidence rates in paediatric patients were lower than those in adult patients. TE was associated with a reduced systolic function in paediatric patients with LVNC.

Indexed as

ThromboembolismVentricular Function, LeftAdultChildHeart VentriclesHumansRisk FactorsStroke Volumecardiomyopathiesheart failuresystematic reviews as topic

Identifiers

PMID35613828
PMCPMC9134208
OpenAlexW4281560982

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.