Evidence map›Paper›PMID 35613417›Full record

ArticleJMIR formative research2022

A Scalable Risk-Scoring System Based on Consumer-Grade Wearables for Inpatients With COVID-19: Statistical Analysis and Model Development.

Simon Föll, Adrian Lison, Martin Maritsch, Karsten Klingberg, Vera Lehmann, Thomas Züger, David Srivastava, Sabrina Jegerlehner, Stefan Feuerriegel, Elgar Fleisch and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR formative research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04357834 (Wearable-based COVID-19 Markers for Prediction of Clinical Trajectories. The WAVE Study.), which is not on this map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04357834 completednot on this map

Wearable-based COVID-19 Markers for Prediction of Clinical Trajectories. The WAVE Study.

TypeobservationalSponsorInsel Gruppe AG, University Hospital BernRan2020 to 2021Enrolled46ConditionsCOVID, COVID 19, SARS-CoV 2ArmsEquipment with smartwatch throughout hospital stay on the general ward
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Simon Föll *Department of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0002-4364-4282
Adrian Lison *Department of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0002-6822-8437
Martin Maritsch *Department of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-9920-0587
Karsten Klingberg *Department of Emergency Medicine, Inselspital, Bern, University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-2502-1428
Vera LehmannDepartment of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern, University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-6038-809X
Thomas ZügerDepartment of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-6190-7405
David SrivastavaDepartment of Emergency Medicine, Inselspital, Bern, University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-4744-0463
Sabrina JegerlehnerDepartment of Emergency Medicine, Inselspital, Bern, University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-0868-0608
Stefan FeuerriegelDepartment of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-7856-8729
Elgar FleischDepartment of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0002-4842-1117
Aristomenis ExadaktylosDepartment of Emergency Medicine, Inselspital, Bern, University Hospital, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-2705-5170
Felix WortmannDepartment of Management, Technology, and Economics, ETH Zürich, Zürich, Switzerland.ORCID https://orcid.org/0000-0001-5034-2023
University of Bern · CHETH Zurich · CHUniversity of St.Gallen · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo provide effective care for inpatients with COVID-19, clinical practitioners need systems that monitor patient health and subsequently allow for risk scoring. Existing approaches for risk scoring in patients with COVID-19 focus primarily on intensive care units (ICUs) with specialized medical measurement devices but not on hospital general wards.

objectiveIn this paper, we aim to develop a risk score for inpatients with COVID-19 in general wards based on consumer-grade wearables (smartwatches).

methodsPatients wore consumer-grade wearables to record physiological measurements, such as the heart rate (HR), heart rate variability (HRV), and respiration frequency (RF). Based on Bayesian survival analysis, we validated the association between these measurements and patient outcomes (ie, discharge or ICU admission). To build our risk score, we generated a low-dimensional representation of the physiological features. Subsequently, a pooled ordinal regression with time-dependent covariates inferred the probability of either hospital discharge or ICU admission. We evaluated the predictive performance of our developed system for risk scoring in a single-center, prospective study based on 40 inpatients with COVID-19 in a general ward of a tertiary referral center in Switzerland.

resultsFirst, Bayesian survival analysis showed that physiological measurements from consumer-grade wearables are significantly associated with patient outcomes (ie, discharge or ICU admission). Second, our risk score achieved a time-dependent area under the receiver operating characteristic curve (AUROC) of 0.73-0.90 based on leave-one-subject-out cross-validation.

conclusionsOur results demonstrate the effectiveness of consumer-grade wearables for risk scoring in inpatients with COVID-19. Due to their low cost and ease of use, consumer-grade wearables could enable a scalable monitoring system.

trial registrationClinicaltrials.gov NCT04357834; https://www.clinicaltrials.gov/ct2/show/NCT04357834.

Indexed as

Bayesian survival analysisCOVID-19digital healthgeneral wardhospitalmeasurement instrumentmeasurement toolpatient monitoringremote monitoringremote patient monitoringrisk scorerisk scoringscalablesmart devicesmartwatchsmartwatcheswearablewearable devices

Identifiers

PMID35613417
PMCPMC9217156
OpenAlexW4282946877

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.