Evidence map›Paper›PMID 35613331›Full record

ReviewChemical reviews2022

The Synthesis and Glycoside Formation of Polyfluorinated Carbohydrates.

Kler Huonnic, Bruno Linclau

Open access · hybridAbstract readReview
In one paragraph

Review in Chemical reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 38 citations in OpenAlex.

  1. Selective fluorination of Fc glycans enhances antibody-mediated effector functions.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Synthetic Access to Fluorinated Analogs of a KnownACS organic & inorganic Au · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Synthesis of Fluorinated Glycotope Mimetics Derived fromInternational journal of molecular sciences · 2025
    Article
  8. Borane-Mediated Highly Secondary Selective Deoxyfluorination of Alcohols.Angewandte Chemie (International ed. in English) · 2025
    Article
  9. Review
  10. Article
  11. Obtaining PureThe Journal of organic chemistry · 2023
    Article
  12. Review
  13. Versatile Fluorine-Containing Building Blocks:Molecules (Basel, Switzerland) · 2022
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Kler HuonnicSchool of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, U.K.ORCID 0000-0002-8531-2307
Bruno LinclauSchool of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, U.K.ORCID 0000-0001-8762-0170
Ghent University · BEUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fluorinated carbohydrates have found many applications in the glycosciences. Typically, these contain fluorination at a single position. There are not many applications involving polyfluorinated carbohydrates, here defined as monosaccharides in which more than one carbon has at least one fluorine substituent directly attached to it, with the notable exception of their use as mechanism-based inhibitors. The increasing attention to carbohydrate physical properties, especially around lipophilicity, has resulted in a surge of interest for this class of compounds. This review covers the considerable body of work toward the synthesis of polyfluorinated hexoses, pentoses, ketosugars, and aminosugars including sialic acids and nucleosides. An overview of the current state of the art of their glycosidation is also provided.

Indexed as

CarbohydratesFluorineCarbonHexosesMonosaccharidesNucleosidesPentosesSialic AcidsCarbohydratesCarbonFluorineHexosesMonosaccharidesNucleosidesPentosesSialic Acids

Identifiers

PMID35613331
PMCPMC9615045
OpenAlexW4281491532

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.