Evidence map›Paper›PMID 35613268›Full record

ArticleScience advances2022

E-site drug specificity of the human pathogen

Yury Zgadzay, Olga Kolosova, Artem Stetsenko, Cheng Wu, David Bruchlen, Konstantin Usachev, Shamil Validov, Lasse Jenner, Andrey Rogachev, Gulnara Yusupova and 3 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

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  6. Mechanism of read-through enhancement by aminoglycosides and mefloquine.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  9. Intricate ribosome composition and translational reprogramming in epithelial-mesenchymal transition.Proceedings of the National Academy of Sciences of the United States of America · 2024
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  11. Imaging-Based Screening Identifies Modulators of theAntimicrobial agents and chemotherapy · 2023
    Article
  12. Imaging-based screening identifies modulators of thebioRxiv : the preprint server for biology · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 4 countries.

Yury ZgadzayDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France.ORCID 0000-0002-0801-4656
Olga KolosovaDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France.ORCID 0000-0003-1348-2152
Artem StetsenkoGroningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, Netherlands.ORCID 0000-0003-3032-3794
Cheng WuDepartment of Biology, Texas A&M University, College Station, TX, USA.ORCID 0000-0003-2340-3788
David BruchlenDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France.ORCID 0000-0002-3729-9531
Konstantin UsachevLaboratory of Structural Biology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.ORCID 0000-0002-6331-7764
Shamil ValidovLaboratory of Structural Biology, Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.ORCID 0000-0002-9441-409X
Lasse JennerDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France.ORCID 0000-0003-3917-8853
Andrey RogachevMoscow Institute of Physics and Technology, Dolgoprudny, Russia.ORCID 0000-0003-2872-7976
Gulnara YusupovaDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France.
Matthew S SachsDepartment of Biology, Texas A&M University, College Station, TX, USA.ORCID 0000-0001-9891-9223
Albert GuskovGroningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, Netherlands.ORCID 0000-0003-2340-2216
Marat YusupovDepartment of Integrated Structural Biology, Institute of Genetics and Molecular and Cellular Biology, University of Strasbourg, Illkirch, France.ORCID 0000-0001-5544-0597
Institut de génétique et de biologie moléculaire et cellulaire · FRKazan Federal University · RUMoscow Institute of Physics and Technology · RURussian Academy of Sciences · RUTexas A&M University · USUniversity of Groningen · NL

Funding

Determining genetic signatures of the cryptococcal response to Zoloft by an integrated approach combining transcriptome, translatome and genetic screensR21AI138158 · NIAID · TEXAS A&M UNIVERSITY · PI LIN, XIAORONG, SACHS, MATTHEW STEVEN · 2018 to 2019
$395k
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antifungal AgentsCandida albicansBinding SitesCryoelectron MicroscopyHumansRibosomesAntifungal Agents

Identifiers

PMID35613268
PMCPMC9132455
OpenAlexW4281476264

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.