Evidence map›Paper›PMID 35613266›Full record

ArticleScience advances2022

Selective endocytosis of Ca

Domenico Azarnia Tehran, Gaga Kochlamazashvili, Niccolò P Pampaloni, Silvia Sposini, Jasmeet Kaur Shergill, Martin Lehmann, Natalya Pashkova, Claudia Schmidt, Delia Löwe, Hanna Napieczynska and 6 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Simvastatin rescues cognitive impairment in an AβNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
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  6. Atomistic mechanisms of calcium permeation modulated by Q/R editing and selectivity filter mutations in GluA2 AMPA receptors.Proceedings of the National Academy of Sciences of the United States of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Domenico Azarnia TehranLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0001-8955-7240
Gaga KochlamazashviliLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Niccolò P PampaloniLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0002-4066-0295
Silvia SposiniUniversity of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France.ORCID 0000-0001-7681-8376
Jasmeet Kaur ShergillLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0001-5506-2995
Martin LehmannLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0002-8370-6353
Natalya PashkovaDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-2191-4683
Claudia SchmidtLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Delia LöweLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Hanna NapieczynskaAnimal Phenotyping, Max Delbrück Center for Molecular Medicine, Robert-Roessle-Straße 10, 13125 Berlin, Germany.
Arnd HeuserAnimal Phenotyping, Max Delbrück Center for Molecular Medicine, Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0002-3334-960X
Andrew J R PlestedLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0001-6062-0832
David PerraisUniversity of Bordeaux, Interdisciplinary Institute for Neuroscience, UMR 5297, Bordeaux, France.ORCID 0000-0002-5878-5408
Robert C PiperDepartment of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0001-9995-5699
Volker HauckeLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0003-3119-6993
Tanja MaritzenLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Robert-Roessle-Straße 10, 13125 Berlin, Germany.ORCID 0000-0003-4993-0340
Leibniz-Forschungsinstitut für Molekulare Pharmakologie · DECentre National de la Recherche Scientifique · FRHumboldt-Universität zu Berlin · DEMax Delbrück Center · DEUniversity of Iowa · USUniversity of Kaiserslautern · DE

Funding

Ubiquitin-Dependent Sorting in Endosomes and the TGNR01GM058202 · NIGMS · UNIVERSITY OF IOWA · PI PIPER, ROBERT C · 1998 to 2025
$8.9M
NIGMS NIH HHS R01 GM058202
6 · The paper itself

Abstract

AMPA-type glutamate receptors (AMPARs) mediate fast excitatory neurotransmission, and the plastic modulation of their surface levels determines synaptic strength. AMPARs of different subunit compositions fulfill distinct roles in synaptic long-term potentiation (LTP) and depression (LTD) to enable learning. Largely unknown endocytic mechanisms mediate the subunit-selective regulation of the surface levels of GluA1-homomeric Ca

Indexed as

Alzheimer DiseaseAnimalsEndocytosisMammalsNeuronal PlasticityReceptors, AMPARisk FactorsReceptors, AMPA

Identifiers

PMID35613266
PMCPMC9132451
OpenAlexW4281491015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.