ArticleArquivos brasileiros de cardiologia2022
Hormone therapy and Hypertension in Postmenopausal Women: Results from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Article in Arquivos brasileiros de cardiologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 14 citations in OpenAlex.
- Risk Factors Associated with Systemic Arterial Hypertension in Postmenopausal Women Engaged in Resistance Training: A Cross-Sectional Observational Study.International journal of environmental research and public health · 2026Observational
- Impact of Obesity on Patients with Resistant and Refractory Arterial Hypertension: A Cross-Sectional Study.Arquivos brasileiros de cardiologia · 2026Article
- Overcoming Women's Lifelong Hormonal Rollercoaster: A Turning Point for Cardiovascular Prevention.Arquivos brasileiros de cardiologia · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHypertension is a major risk factor for cardiovascular morbidity and mortality in post-menopausal women. Although menopausal hormone therapy (MHT) is a very effective treatment for vasomotor symptoms during this period, the influence of this therapy on blood pressure is not yet clear.
objectiveTo evaluate the relationship between the use of MHT and hypertension in participants of the ELSA-Brasil.
methodsA cross-sectional study using the baseline ELSA-Brasil data in a cohort of 2,138 women who had experienced natural menopause. This study analyzed hypertension, defined as arterial pressure ≥140/90 mmHg or previous antihypertensive use, and use of MHT, with participants being classified into never, past, and current users. Associations were assessed using an adjusted logistic regression model, with statistical significance set at p<0.05.
resultsOverall, 1,492 women (69.8%) had never used MHT, 457 (21.4%) had used it in the past, and 189 (8.8%) were current users. The use of MHT was more common in women who had a body mass index (BMI) <25 kg/m2and triglyceride levels <150 mg/dl, and who were physically less inactive, non-smokers, and non-diabetics. Current MHT users were less likely to have hypertension (OR=0.59; 95% CI: 0.41-0.85) compared to those who had never used MHT. In most cases, MHT was started at or before 59 years of age, within 10 years of becoming menopausal, and its use lasted for up to five years.
conclusionCurrent MHT use was not related to hypertension, particularly in healthy women and in those under 60 years of age.
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