Evidence map›Paper›PMID 35613138›Full record

ArticlePloS one2022

Multilevel analysis of predictors of multiple indicators of childhood vaccination in Nigeria.

Justice Moses K Aheto, Oliver Pannell, Winfred Dotse-Gborgbortsi, Mary K Trimner, Andrew J Tatem, Dale A Rhoda, Felicity T Cutts, C Edson Utazi

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

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  6. Serological evaluation of immunity againstHuman vaccines & immunotherapeutics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Justice Moses K AhetoWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.ORCID 0000-0003-1384-2461
Oliver PannellWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Winfred Dotse-GborgbortsiWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Mary K TrimnerBiostat Global Consulting, Worthington, OH, United States of America.
Andrew J TatemWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
Dale A RhodaBiostat Global Consulting, Worthington, OH, United States of America.ORCID 0000-0003-0948-1368
Felicity T CuttsDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
C Edson UtaziWorldPop, School of Geography and Environmental Science, University of Southampton, Southampton, United Kingdom.
University of Southampton · GBLondon School of Hygiene & Tropical Medicine · GBUniversity of Ghana · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubstantial inequalities exist in childhood vaccination coverage levels. To increase vaccine uptake, factors that predict vaccination coverage in children should be identified and addressed.

methodsUsing data from the 2018 Nigeria Demographic and Health Survey and geospatial data sets, we fitted Bayesian multilevel binomial and multinomial logistic regression models to analyse independent predictors of three vaccination outcomes: receipt of the first dose of Pentavalent vaccine (containing diphtheria-tetanus-pertussis, Hemophilus influenzae type B and Hepatitis B vaccines) (PENTA1) (n = 6059) and receipt of the third dose having received the first (PENTA3/1) (n = 3937) in children aged 12-23 months, and receipt of measles vaccine (MV) (n = 11839) among children aged 12-35 months.

resultsFactors associated with vaccination were broadly similar for documented versus recall evidence of vaccination. Based on any evidence of vaccination, we found that health card/document ownership, receipt of vitamin A and maternal educational level were significantly associated with each outcome. Although the coverage of each vaccine dose was higher in urban than rural areas, urban residence was not significant in multivariable analyses that included travel time. Indicators relating to socio-economic status, as well as ethnic group, skilled birth attendance, lower travel time to the nearest health facility and problems seeking health care were significantly associated with both PENTA1 and MV. Maternal religion was related to PENTA1 and PENTA3/1 and maternal age related to MV and PENTA3/1; other significant variables were associated with one outcome each. Substantial residual community level variances in different strata were observed in the fitted models for each outcome.

conclusionOur analysis has highlighted socio-demographic and health care access factors that affect not only beginning but completing the vaccination series in Nigeria. Other factors not measured by the DHS such as health service quality and community attitudes should also be investigated and addressed to tackle inequities in coverage.

Indexed as

Immunization ProgramsVaccinationBayes TheoremChildHepatitis B VaccinesHumansInfantMeasles VaccineMultilevel AnalysisNigeriaHepatitis B VaccinesMeasles Vaccine

Identifiers

PMID35613138
PMCPMC9132327
OpenAlexW4281552212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.