SynthesisThe British journal of surgery2022
Risks for donors associated with living kidney donation: meta-analysis.
Synthesis in The British journal of surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Comparison of Laparoscopic and Hand-assisted Live Donor Nephrectomy: An Analysis of NSQIP Transplant.Transplantation direct · 2026Article
- Acute kidney injury in urological conditions.Asian biomedicine : research, reviews and news · 2026Review
- Long-Term Outcomes Across Age and Risk Profiles in a Caucasian Living Kidney Donor Cohort.Transplant international : official journal of the European Society for Organ Transplantation · 2026Article
- Outcomes of living donor kidney transplantation from extended criteria donors to extended criteria recipients: A retrospective cohort study.World journal of transplantation · 2025Article
- Impact of donating the larger kidney by CT volumetry on the kidney function, 5-years after living donation.World journal of urology · 2025Article
- 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2025Review
- The utility of split function testing in determining recovery of glomerular filtration rate after living kidney donation: a cohort study.BMC nephrology · 2025Article
- Non-Maleficence toward Young Kidney Donors: A Call for Stronger Ethical Standards and Associated Factors in Multidisciplinary Nephrology Teams.Nursing reports (Pavia, Italy) · 2024Article
- Lean body mass in living kidney donors impacts postoperative renal function.World journal of urology · 2024Article
- Article
- 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.Circulation · 2024Review
- The Ultrasound Renal Stress Test for the Assessment of Functional Renal Reserve in Kidney Transplantation: A Pilot Study in Living Donors.Journal of clinical medicine · 2024Article
- Longitudinal Trajectories of Estimated Glomerular Filtration Rate in a European Population of Living Kidney Donors.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Risk factors for lower renal compensation after nephrectomy: an analysis of living kidney donors in an Amazonian cohort.Jornal brasileiro de nefrologia · 2024Observational
- Survival Advantage Comparing Older Living Donor Versus Standard Criteria Donor Kidney Transplants.Transplant international : official journal of the European Society for Organ Transplantation · 2024Article
- Eliminating Race From eGFR Calculations: Impact on Living Donor Programs.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLiving kidney donation risk is likely to differ according to donor's demographics. We aimed to analyse the effects of age, sex, body mass index (BMI) and ethnicity.
methodsA systematic review and meta-analysis was undertaken of the effects of preoperative patient characteristics on donor kidney function outcomes, surgical complications, and hypertension.
results5129 studies were identified, of which 31 met the inclusion criteria, mainly from the USA and Europe. The estimated glomerular filtration rate (eGFR) in donors aged over 60 years was a mean of 9.54 ml per min per 1.73 m2 lower than that of younger donors (P < 0.001). Female donors had higher relative short- and long-term survival. BMI of over 30 kg/m2 was found to significantly lower the donor's eGFR 1 year after donation: the eGFR of obese donors was lower than that of non-obese patients by a mean of -2.70 (95 per cent c.i. -3.24 to -2.15) ml per min per 1.73 m2 (P < 0.001). Obesity was also associated with higher blood pressure both before and 1 year after donation, and a higher level of proteinuria, but had no impact on operative complications. In the long term, African donors were more likely to develop end-stage renal disease than Caucasians.
conclusionObesity and male sex were associated with inferior outcomes. Older donors (aged over 60 years) have a larger eGFR decline than younger donors, and African donors have a higher incidence of ESRD than Caucasians.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.