Evidence map›Paper›PMID 35612822›Full record

ArticleThe FEBS journal2022

Atomic solution structure of Mycobacterium abscessus F-ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor.

Joon Shin, Amaravadhi Harikishore, Chui Fann Wong, Priya Ragunathan, Thomas Dick, Gerhard Grüber

Open access · bronzeAbstract read
In one paragraph

Article in The FEBS journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Toward better cures forClinical microbiology reviews · 2024
    Review
  2. Cryo-EM reveals transition states of the Acinetobacter baumannii FFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2024
    Article
  3. ATP binding by an FFrontiers in molecular biosciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Joon ShinSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Amaravadhi HarikishoreSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Chui Fann WongSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Priya RagunathanSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.
Thomas DickCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ, USA.
Gerhard GrüberSchool of Biological Sciences, Nanyang Technological University, Singapore, Singapore.ORCID 0000-0002-5730-8319
Nanyang Technological University · SGGeorgetown University · US

Funding

Discovery of novel lead-target pairs and identification of all-oral bactericidal drug regimens for Mycobacterium abscessus lung diseaseR01AI132374 · NIAID · RBHS-NEW JERSEY MEDICAL SCHOOL · PI Thomas Dick · 2018 to 2026
$7.0M
NIAID NIH HHS R01 AI132374
6 · The paper itself

Abstract

Mycobacterium abscessus (Mab) is a nontuberculous mycobacterium of increasing clinical relevance. The rapidly growing opportunistic pathogen is intrinsically multi-drug-resistant and causes difficult-to-cure lung disease. Adenosine triphosphate, generated by the essential F

Indexed as

Mycobacterium abscessusProton-Translocating ATPasesAdenosine TriphosphateAmino AcidsBacterial ProteinsEpitopesProtein ConformationProtein SubunitsProtonsAdenosine TriphosphateAmino AcidsBacterial ProteinsEpitopesProtein SubunitsProtonsProton-Translocating ATPasesbioenergeticsF-ATP synthasemycobacteriaNMR spectroscopyoxidative phosphorylationε enzyme inhibitor

Identifiers

PMID35612822
PMCPMC10609657
OpenAlexW4281478353

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.