ArticleAdvances in experimental medicine and biology2022
Non-surgical Periodontal Treatment: SRP and Innovative Therapeutic Approaches.
Article in Advances in experimental medicine and biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Does Probiotic Therapy Improve Periodontal Treatment Outcomes in Smoking Patients? A Systematic Review of Randomized Clinical Trials.Probiotics and antimicrobial proteins · 2026Pooled it
- Root Cementum Molecular Structure and Its Role in Maintaining Oral Health-Systematic Review.International journal of molecular sciences · 2025Pooled it
- Therapeutic potential of boric acid as a local drug delivery agent in periodontitis: a comprehensive systematic review and meta-analysis.BMC oral health · 2025Pooled it
- Clinical effects of erythritol, glycine and trehalose as subgingival air-polishing powders on non-surgical periodontal treatment:a systematic review with meta-analysis of randomized controlled trials.Frontiers in physiology · 2025Pooled it
- Therapeutic Strategies and Genetic Implications for Periodontal Disease Management: A Systematic Review.International journal of molecular sciences · 2024Pooled it
- Clinical efficacy of high versus low intensity diode laser as an adjunct to non-surgical periodontal therapy in periodontitis: randomized controlled clinical trial.Scientific reports · 2026Trial
- Clinical and radiographic evaluation of melatonin and chitosan loaded nanoparticles in the treatment of periodontal intra-bony defects: A Randomized controlled clinical trial.Clinical oral investigations · 2025Trial
- Guided biofilm therapy versus conventional protocol-clinical outcomes in non-surgical periodontal therapy.BMC oral health · 2024Trial
- Impact of Adjunctive Air-Polishing on Periodontal Status in Patients with Low Vitamin DJournal of clinical medicine · 2025Article
- Chitosan-Based Nanoencapsulation of Mānuka Oil for Periodontal Treatment.International journal of molecular sciences · 2025Review
- [Defect modification of calcium silicate and its application in oral bacteriostasis and tooth remineralization].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2025Article
- The effect of bacteriophage in oral health: developing microbial ecology and emerging potential therapeutic target.Future microbiology · 2025Review
- Propolis mouthwashes efficacy in managing gingivitis and periodontitis: a systematic review of the latest findings.BDJ open · 2025Article
- Muco-Adhesive Hydrogels-Based Exosome Delivery for Periodontal Tissue Regeneration and Inflammation Reduction: A Review.International journal of nanomedicine · 2025Review
- Article
- Early detection of cardiovascular risk markers through non-invasive ultrasound methodologies in periodontitis patients.Open medicine (Warsaw, Poland) · 2024Review
- Nanoparticles in Periodontitis Therapy: A Review of the Current Situation.International journal of nanomedicine · 2024Review
- Article
- Subgingival Use of Air-Polishing Powders: Status of Knowledge: A Systematic Review.Journal of clinical medicine · 2023Review
- Obesity Is Associated with the Severity of Periodontal Inflammation Due to a Specific Signature of Subgingival Microbiota.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Periodontitis is a major public health problem, that can have local and systemic consequences ranging from tooth loss to the aggravation of other chronic diseases. The consequences of which have an impact on patient's overall general health and quality of life. Periodontal treatments include a large range of techniques and concepts from plaque control to periodontal debridement, surgery and regeneration. Regardless of the treatment proposed, it always begins with the same first essential simple step that is etiological therapy which includes oral hygiene management and the control of periodontal risk factors. The aim of this first step, presented in this chapter, consists mainly in reducing oral bacterial load and inflammation by the means of daily oral hygiene methods and sub-gingival biofilm disruption. Although understanding of the pathogenesis and molecular and cellular mechanisms involved in periodontitis has increased, treatment wise, non-surgical debridement remains the keystone of every periodontal treatment and supportive periodontal therapy. Once risk factors are monitored and plaque control mastered by the patient, root instrumentation can be performed with hand or power-driven instruments. However effective, sub-gingival biofilm disruption has some limits and can be improved with adjunctive therapies such as antiseptics, antibiotics, air polishing or other emerging devices and therapies. Unfortunately, the lack of clear clinical guidelines, concerning these adjunctive therapies, still remains, thus pointing out the necessity of more standardized clinical studies. Also, if some patients can return to a healthy periodontal state, most periodontal patients will remain at periodontal risk for life. Proper assessment of the patient's periodontal risk will help establish correct monitoring of patients successfully treated for their periodontal disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.