Evidence map›Paper›PMID 35612776›Full record

ArticleProbiotics and antimicrobial proteins2022

Assessing the Activity of Antimicrobial Peptides Against Common Marine Bacteria Located in Rotifer (Brachionus plicatilis) Cultures.

Chelsea Woods, Lindsey Woolley, Gavin Partridge, Mengqi Chen, Evan F Haney, Robert E W Hancock, Nicky Buller, Andrew Currie

Abstract read
In one paragraph

Article in Probiotics and antimicrobial proteins, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chelsea WoodsCollege of Science, Murdoch University, Engineering & Education, HealthPerth, WA, Australia. cheslea.woodsnielsen@gmail.com.
Lindsey WoolleyCollege of Science, Murdoch University, Engineering & Education, HealthPerth, WA, Australia.
Gavin PartridgeCollege of Science, Murdoch University, Engineering & Education, HealthPerth, WA, Australia.
Mengqi ChenDepartment of Primary Industries and Regional Development, Fremantle, Perth, WA, 6160, Australia.
Evan F HaneyCentre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
Robert E W HancockCentre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
Nicky BullerCollege of Science, Murdoch University, Engineering & Education, HealthPerth, WA, Australia.
Andrew CurrieCentre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rotifers are used as the first feed for marine fish larvae and are grown in large cultures that have high loads of organic matter and heterotrophic bacteria; these bacteria are passed on to the developing fish larvae and can potentially lead to bacterial infections. A modified minimum inhibitory concentration (MIC) protocol for antimicrobial peptides was used to determine the potency of ten antimicrobial peptides (AMPs) in artificial seawater relevant to a rotifer culture (salinity of 25‰) against common marine pathogens. All of the AMPs had antimicrobial activity against the bacterial isolates when the salt concentration was approximately zero. However, in high salt concentrations, the majority of the AMPs had an MIC value greater than 65 µg mL

Indexed as

Antimicrobial PeptidesRotiferaAnimalsLarvaSeawaterAntimicrobial PeptidesAntibacterial activityAntimicrobial peptidesBrachionus plicatilisMinimum inhibitory concentrationProbiotics

Identifiers

PMID35612776
PMCPMC9246773

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.