Evidence map›Paper›PMID 35612567›Full record

ArticleDento maxillo facial radiology2022

Convolutional neural network-based automatic cervical vertebral maturation classification method.

Haizhen Li, Yanlong Chen, Qing Wang, Xu Gong, Yi Lei, Jialiang Tian, Xuemei Gao

Abstract read
In one paragraph

Article in Dento maxillo facial radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Objective Assessment of Bone Age in Orthodontics: A Scoping Review.Journal of pharmacy & bioallied sciences · 2025
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  14. DC-YOLOv5-based target detection algorithm for cervical vertebral maturation.Physical and engineering sciences in medicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haizhen LiDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing, P.R. China.
Yanlong ChenDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing, P.R. China.
Qing WangDepartment of Automation, Tsinghua University, No.30 Shuangqing Road, Haidian District, Beijing, P.R. China.
Xu GongDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing, P.R. China.
Yi LeiSchool of Software Engineering, Faculty of Information Technology, No.100 Pingleyuan, Chaoyang District, Beijing, P.R. China.
Jialiang TianSchool of Artificial Intelligence, Beijing University of Posts and Telecommunications, No.10 Xitucheng Road, Haidian District, Beijing, P.R. China.
Xuemei GaoDepartment of Orthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun South Avenue, Haidian District, Beijing, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to develop a fully automated artificial intelligence-aided cervical vertebral maturation (CVM) classification method based on convolutional neural networks (CNNs) to provide an auxiliary diagnosis for orthodontists.

methodsThis study consisted of cephalometric images from patients aged between 5 and 18 years. After grouping them into six cervical stages (CSs) by orthodontists, a data set was constructed for analyzing CVM using CNNs. The data set was divided into training, validation, and test sets in the ratio of 70, 15, and 15%. Four CNN models namely, VGG16, GoogLeNet, DenseNet161, and ResNet152 were selected as the candidate models. After training and validation, the models were evaluated to determine which of them is most suitable for CVM analysis. Heat maps were analyzed for a deeper understanding of what the CNNs had learned.

resultsThe final classification accuracy ranking was ResNet152>DenseNet161>GoogLeNet>VGG16, as evaluated on the test set. ResNet152 proved to be the best model among the four models for CVM classification with a weighted κ of 0.826, an average AUC of 0.933 and total accuracy of 67.06%. The F1 score rank for each subgroup was: CS6>CS1>CS4>CS5>CS3>CS2. The area of the third (C3) and fourth (C4) cervical vertebrae were activated when CNNs were assessing the images.

conclusionCNN models proved to be a convenient, fast and reliable method for CVM analysis. CNN models have the potential to provide automatic auxiliary diagnostic tools in the future.

Indexed as

Artificial IntelligenceCervical VertebraeAdolescentCephalometryChildChild, PreschoolHumansNeural Networks, ComputerArtificial intelligenceCervical vertebral maturation analysisConvolutional neural network

Identifiers

PMID35612567
PMCPMC10043621

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.