Evidence map›Paper›PMID 35612547›Full record

ArticleThe British journal of radiology2022

Nomogram based on ultrasound radiomics score and clinical variables for predicting histologic subtypes of epithelial ovarian cancer.

Fei Yao, Jie Ding, Feng Lin, Xiaomin Xu, Qi Jiang, Li Zhang, Yanqi Fu, Yunjun Yang, Li Lan

Abstract read
In one paragraph

Article in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Radiomics and radiogenomics in ovarian cancer: a review with a focus on ultrasound applications.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Review
  5. Article
  6. Article
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  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fei YaoDepartment of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Jie DingDepartment of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Feng LinDepartment of Gynecology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Xiaomin XuDepartment of Ultrasound imaging, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Qi JiangSchool of First Clinical Medicine, Wenzhou Medical University, Wenzhou, China.
Li ZhangSchool of First Clinical Medicine, Wenzhou Medical University, Wenzhou, China.
Yanqi FuSchool of First Clinical Medicine, Wenzhou Medical University, Wenzhou, China.
Yunjun YangDepartment of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Li LanDepartment of Ultrasound imaging, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.ORCID 0000-0003-1255-5102

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveOvarian cancer is one of the most common causes of death in gynecological tumors, and its most common type is epithelial ovarian cancer (EOC). This study aimed to establish a radiomics signature based on ultrasound images to predict the histopathological types of EOC.

methodsOverall, 265 patients with EOC who underwent preoperative ultrasonography and surgery were eligible. They were randomly sorted into two cohorts (training cohort: test cohort = 7:3). We outlined the region of interest of the tumor on the ultrasound images of the lesion. Then, the radiomics features were extracted. Clinical, Rad-score and combined models were constructed based on the least absolute shrinkage, selection operator, and logistic regression analysis. The performance of the models was evaluated using receiver operating characteristic curves and decision curve analysis (DCA). A nomogram was formulated based on the combined prediction model.

resultsThe combined model had good performance in predicting EOC histopathological types, with an AUC of 0.83 (95% CI: 0.77-0.90) and 0.82 (95% CI: 0.71-0.93) in the training and test cohorts, respectively. The calibration curves showed that the nomogram estimation was consistent with the actual observations. DCA also verified the clinical value of the combined model.

conclusionsThe combined model containing clinical and ultrasound radiomics features showed an excellent performance in predicting type I and type II EOC. ADVANCES IN KNOWLEDGE: This study presents the first application of ultrasound radiomics features to distinguish EOC histopathological types. The proposed clinical-radiomics nomogram could help gynecologists non-invasively identify EOC types before surgery.

Indexed as

NomogramsOvarian NeoplasmsCarcinoma, Ovarian EpithelialFemaleHumansRetrospective StudiesUltrasonography

Identifiers

PMID35612547
PMCPMC10162053

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.