Evidence map›Paper›PMID 35612546›Full record

ArticleJournal of the American Geriatrics Society2022

Emergency and post-emergency care of older adults with Alzheimer's disease/Alzheimer's disease related dementias.

Jacob D Hill, Abigail M Schmucker, Nina Siman, Keith S Goldfeld, Allison M Cuthel, Joshua Chodosh, Jean-Baptiste Bouillon-Minois, Corita R Grudzen

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06357195 (Implementation of DIAMOND-Lewy Guidelines for Emergency Department Antipsychotic Use in Older Patients With Cognitive and Movement Disorders), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06357195 active not recruitingnot on this mapstarted 2024, after this paper: background citation

Implementation of DIAMOND-Lewy Guidelines for Emergency Department Antipsychotic Use in Older Patients With Cognitive and Movement Disorders

TypeobservationalSponsorOhio State UniversityRan2024 to 2026Enrolled1,000ConditionsEmergency Psychiatric, Cognition Disorder, Movement Disorders, Antipsychotics and Neuroleptics Toxicity
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Bedside cognitive screening to detect dementia and predict poor outcomes in hospitals.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Article
  5. Article
  6. Emergency Care for Persons Living with Dementia.Emergency medicine clinics of North America · 2025
    Review
  7. Physical Activity and Acute Care Utilization Among Older Adults With Mild Cognitive Impairment and Dementia.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. 2024 Alzheimer's disease facts and figures.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Article
  14. Review
  15. Article
  16. Observational
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Jacob D HillRonald O. Perelman Department of Emergency Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Abigail M SchmuckerDepartment of Internal Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2813-1868
Nina SimanRonald O. Perelman Department of Emergency Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Keith S GoldfeldDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Allison M CuthelRonald O. Perelman Department of Emergency Medicine, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-9978-6706
Joshua ChodoshDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Jean-Baptiste Bouillon-MinoisRonald O. Perelman Department of Emergency Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Corita R GrudzenRonald O. Perelman Department of Emergency Medicine, New York University Grossman School of Medicine, New York, New York, USA.
New York University · USCentre Hospitalier Universitaire de Clermont-Ferrand · FRNYU Langone Health · USUniversity of Pennsylvania · US

Funding

Research Education ComponentP30AG066512 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Mary Sherman Mittelman · 2020 to 2026
$28.4M
NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)U24AT009676 · NCCIH · DUKE UNIVERSITY · PI LESLEY H CURTIS, Adrian Hernandez · 2017 to 2026
$21.5M
Primary Palliative Care for Emergency MedicineUH3AT009844 · NCCIH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GOLDFELD, KEITH, GRUDZEN, CORITA R · 2019 to 2022
$7.9M
Primary Palliative Care for Emergency MedicineUG3AT009844 · NCCIH · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GRUDZEN, CORITA R · 2018 to 2018
$984k
NCCIH NIH HHS U24 AT009676NCCIH NIH HHS UG3 AT009844NCCIH NIH HHS UH3 AT009844NIA NIH HHS P30 AG066512
6 · The paper itself

Abstract

backgroundThe emergency department (ED) is a critical juncture in the care of persons living with dementia (PLwD), as they have a high rate of hospital admission, ED revisits, and subsequent inpatient stays. We examine ED disposition of PLwD compared with older adults with non-dementia chronic disease as well as healthcare utilization and survival.

methodsMedicare claims data were used to identify community-dwelling older adults 66+ years old from 34 hospitals with either Alzheimer's disease/Alzheimer's disease related dementias (AD/ADRD) or a non-AD/ADRD chronic condition between January 1, 2014, and December 31, 2018. We compared ED disposition at the index visit, as well as healthcare utilization and mortality in the 12 months following an index ED visit, and adjusted for age, gender, and risk of mortality.

resultsThere were 29,626 patients in the AD/ADRD sample, and 317,046 in the comparison sample. The AD/ADRD sample was older (82.4 years old [SD: 8.2] vs. 76.0 years old [SD: 7.7]) and had more female patients (59.9% vs. 54.7%). The AD/ADRD sample was more likely to experience ED disposition to acute care (OR 1.039, p < 0.001, 95% CI 1.029-1.050), to have an ED revisit (OR 1.077, p < 0.001, 95% CI 1.066-1.087), and an inpatient stay in the subsequent 12 months (OR 1.085, p < 0.001, 95% CI 1.075-1.095). ED disposition to hospice was low in both samples (0.2%). AD/ADRD patients had a higher risk of mortality (OR 1.099, p < 0.001, 95% CI 1.091-1.107) and high short-term mortality (31.9% within 12 months) than those without AD/ADRD (15.3% within 12 months).

conclusionsPLwD who visit the ED have high short-term mortality. Despite this, disposition to acute care, ED revisits, and inpatient stays, rather than hospice, remain the predominant mode of care delivery. Transition directly from the ED to hospice for PLwD is rare.

Indexed as

Alzheimer DiseaseEmergency Medical ServicesHospice CareAgedAged, 80 and overChronic DiseaseFemaleHospitalizationHumansMedicareUnited StatesAlzheimer's diseaseemergency medicinegeriatricshealthcare utilizationMedicare

Identifiers

PMID35612546
PMCPMC9489611
OpenAlexW4281476995

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.