Evidence map›Paper›PMID 35612320›Full record

ArticleDrug delivery2022

Phototherapeutic effect of transformable peptides containing pheophorbide a on colorectal cancer.

Zhiqin Zhang, Kaixin Wang, Manting Liu, Panxiang Hu, Yuchen Xu, Dongge Yin, Yuchang Yang, Xiaoxv Dong, Changhai Qu, Lu Zhang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Zhiqin ZhangSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.ORCID 0000-0003-2127-6404
Kaixin WangSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Manting LiuSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Panxiang HuSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Yuchen XuSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Dongge YinSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Yuchang YangSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Xiaoxv DongSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Changhai QuSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Lu ZhangDepartment of Biomedical Engineering, Southern University of Science and Technology, Shenzhen, China.
Jian NiSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Xingbin YinSchool of Chinese Material Medical, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNSouthern University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photodynamic therapy (PDT) and photothermal therapy (PTT) have attracted research interest for their noninvasive nature and selective treatment of tumor tissues. They are effective through the generation of reactive oxygen species (ROS) or heat. Nevertheless, several problems, including low bioavailability and long-lasting cutaneous photosensitivity, have limited their clinical application. In this study, we reported an in situ self-assembly strategy that could improve various biological properties of the photosensitizer

Indexed as

Colorectal NeoplasmsNanoparticlesPhotochemotherapyChlorophyllHumansPeptidesPhotosensitizing AgentsReactive Oxygen SpeciesChlorophyllPeptidespheophorbide aPhotosensitizing AgentsReactive Oxygen Speciesbioavailability improvementPhototherapyphotothermal conversion efficiencyself-assembled peptidesupramolecular nanofibrils

Identifiers

PMID35612320
PMCPMC9135428
OpenAlexW4281487124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.