Evidence map›Paper›PMID 35611986›Full record

ArticleBioengineered2022

Long non-coding RNA LINC00616 promotes ferroptosis of periodontal ligament stem cells via the microRNA-370 / transferrin receptor axis.

Hongwei Wang, Xiaotong Qiao, Chao Zhang, Jingyi Hou, Suqing Qi

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Application of mesenchymal stem cells in ferroptosis-related diseases.Journal of molecular medicine (Berlin, Germany) · 2025
    Review
  8. Noncoding RNAs in periodontitis: Progress and perspectives (Review).International journal of molecular medicine · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Hongwei WangDepartment of Orthodontics, Eye Hospital of Hebei, Xingtai, Hebei, China.
Xiaotong QiaoDepartment of Oral Medicine, College of Stomatology, Hebei Medical University, Shijiazhuang, Hebei, China.
Chao ZhangDepartment of Orthodontics, Eye Hospital of Hebei, Xingtai, Hebei, China.
Jingyi HouDepartment of Orthodontics, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
Suqing QiDepartment of Orthodontics, Eye Hospital of Hebei, Xingtai, Hebei, China.
Hebei Eye Hospital · CNCapital Medical University · CNHebei Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was designed to explore the role of lncRNA LINC00616 in the regulation of periodontitis. Cellular functions were measured using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL) assays. The content of reactive oxygen species, Fe

Indexed as

FerroptosisMicroRNAsPeriodontitisRNA, Long NoncodingHumansLipopolysaccharidesPeriodontal LigamentReceptors, TransferrinStem CellsLipopolysaccharidesMicroRNAsMIRN370 microRNA, humanReceptors, TransferrinRNA, Long Noncodingbone marrow mesenchymal stem cellsferroptosisLINC00616miR-370PeriodontitisTFRC

Identifiers

PMID35611986
PMCPMC9276003
OpenAlexW4281481679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.