Evidence map›Paper›PMID 35611916›Full record

ArticleESC heart failure2022

Recombinant human brain natriuretic peptide ameliorates venous return function in congestive heart failure.

Jing-Chao Luo, Yi-Jie Zhang, Dan-Lei Huang, Huan Wang, Ming-Hao Luo, Jun-Yi Hou, Guang-Wei Hao, Ying Su, Guo-Wei Tu, Zhe Luo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jing-Chao LuoDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Yi-Jie ZhangDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Dan-Lei HuangDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Huan WangDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Ming-Hao LuoDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Jun-Yi HouDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Guang-Wei HaoDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Ying SuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Guo-Wei TuDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Zhe LuoDepartment of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai, China.
Sun Yat-sen University · CNFudan University · CNZhongshan Hospital · CNShanghai Pulmonary Hospital · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsRecombinant human brain natriuretic peptide (rh-BNP) is commonly used as a decongestive therapy. This study aimed to investigate the instant effects of rh-BNP on cardiac output and venous return function in post-cardiotomy patients with congestive heart failure (CHF). METHODS AND

resultsTwenty-four post-cardiotomy heart failure patients were enrolled and received a standard loading dose of rh-BNP. Haemodynamic monitoring was performed via a pulmonary artery catheter before and after the administration of rh-BNP. The cardiac output and venous return functions were estimated by depicting Frank-Starling and Guyton curves. After rh-BNP infusion, variables reflecting cardiac congestion and venous return function, such as pulmonary artery wedge pressure, mean systemic filling pressure (Pmsf) and venous return resistance index (VRRI), reduced from 15 ± 3 to 13 ± 3 mmHg, from 32 ± 7 to 28 ± 7 mmHg and from 6.7 ± 2.6 to 5.7 ± 1.8 mmHg min m

conclusionsrh-BNP might ameliorate venous return rather than cardiac output function in post-cardiotomy CHF patients.

Indexed as

Heart FailureNatriuretic Peptide, BrainCardiac OutputHeartHumansStroke VolumeNatriuretic Peptide, BrainCardiac outputCongestive heart failurerh-BNPVenous return

Identifiers

PMID35611916
PMCPMC9288780
OpenAlexW4281475978

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.