Evidence map›Paper›PMID 35611851›Full record

ArticleBioengineered2022

miR-155-5p regulates hypoxia-induced pulmonary artery smooth muscle cell function by targeting PYGL.

Guowen Wang, Xuefang Tao, Linlin Peng

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Biomarkers in COPD-Associated PH/CCP: Circulating Molecules and Cell-Intrinsic Marker.International journal of chronic obstructive pulmonary disease · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Guowen WangDepartment of Respiratory Medicine, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang, China.
Xuefang TaoDepartment of Respiratory Medicine, Affiliated Hospital of Shaoxing University, Shaoxing, Zhejiang, China.
Linlin PengDepartment of Clinical Laboratory, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Shaoxing University · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is a cardiovascular disease that has high incidence and causes massive deaths. miR-155-5p/PYGL pathway was revealed to play a crucial role in PAH by weighted gene co-expression network analysis (WGCNA). The potential mechanism of miR-155-5p in regulating hypoxia-induced pulmonary artery smooth muscle cell (PASMC) function was analyzed through

Indexed as

Glycogen Phosphorylase, Liver FormMicroRNAsPulmonary Arterial HypertensionCell HypoxiaCell MovementCell ProliferationCells, CulturedHumansHypoxia-Inducible Factor 1, alpha SubunitMuscle, Smooth, VascularMyocytes, Smooth MusclePulmonary ArteryVascular Endothelial Growth Factor AGlycogen Phosphorylase, Liver FormHypoxia-Inducible Factor 1, alpha SubunitMicroRNAsMIRN155 microRNA, humanPYGL protein, humanVascular Endothelial Growth Factor Ahypoxia‐induced pulmonary arterial hypertensionmiR-155-5pPYGLWGCNA

Identifiers

PMID35611851
PMCPMC9275946
OpenAlexW4281483211

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.