Evidence map›Paper›PMID 35611691›Full record

ArticleMagnetic resonance in medicine2022

Point-of-care magnetic resonance technology to measure liver fat: Phantom and first-in-human pilot study.

Mark Barahman, Eduardo Grunvald, Pablo J Prado, Alejandro Bussandri, Walter C Henderson, Tanya Wolfson, Kathryn J Fowler, Claude B Sirlin

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Magnetic resonance imaging.Science advances · 2026
    Review
  2. Review
  3. MASLD: What We Have Learned and Where We Need to Go-A Call to Action.Radiographics : a review publication of the Radiological Society of North America, Inc · 2024
    Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mark BarahmanLiver Imaging Group, Department of Radiology, University of California San Diego, San Diego, California, USA.ORCID 0000-0002-2110-7742
Eduardo GrunvaldDivision of General Internal Medicine, Department of Medicine, University of California San Diego, San Diego, California, USA.
Pablo J PradoLivivos, San Diego, California, USA.
Alejandro BussandriLivivos, San Diego, California, USA.
Walter C HendersonLiver Imaging Group, Department of Radiology, University of California San Diego, San Diego, California, USA.
Tanya WolfsonLiver Imaging Group, Department of Radiology, University of California San Diego, San Diego, California, USA.
Kathryn J FowlerLiver Imaging Group, Department of Radiology, University of California San Diego, San Diego, California, USA.
Claude B SirlinLiver Imaging Group, Department of Radiology, University of California San Diego, San Diego, California, USA.
University of California San Diego · US

Funding

Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
NIBIB NIH HHS T32 EB005970
6 · The paper itself

Abstract

purposeTo assess feasibility and accuracy of point-of-care (POC) NMR-proton density fat fraction (PDFF) in phantoms and in a human pilot study in a POC setting.

methodsPOC NMR (LiverScope, Livivos, San Diego CA) PDFF measurements were obtained of certified phantoms with known PDFF values (0%-40%). In an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant prospective human study, a convenience sample of participants from an obesity clinic was enrolled (November 2020 to June 2021). The inclusion criteria required body mass index (BMI) = 27-40 kg/m

resultsPOC NMR-PDFF measurements agreed with known phantom PDFF values (R

conclusionPOC NMR measures PDFF accurately in phantoms and, in a first-in-human pilot study, is feasible and accurate in adults with obesity. Further testing to determine precision and accuracy across larger and more diverse cohorts is needed.

Indexed as

Non-alcoholic Fatty Liver DiseasePoint-of-Care SystemsAdultAgedFemaleHumansLiverMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiddle AgedObesityPilot ProjectsProspective StudiesProtonsReproducibility of ResultsTechnologyProtonsdiffusion contrasthepatic steatosispoint of care magnetic resonanceproton density fat fraction

Identifiers

PMID35611691
PMCPMC9339488
OpenAlexW4281558857

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.