ArticleJournal of clinical microbiology2022
Clinical Outcomes of Treated and Untreated C. difficile PCR-Positive/Toxin-Negative Adult Hospitalized Patients: a Quasi-Experimental Noninferiority Study.
Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Clinical significance of toxin EIA positivity in patients with suspectedJournal of clinical microbiology · 2025Pooled it
- The value of fecal calprotectin inFrontiers in physiology · 2022Pooled it
- Clinical outcomes of toxin-positive versus toxin-negative/NAAT-positive Clostridioides difficile infection in South Korea: a single-center retrospective cohort study.BMC infectious diseases · 2026Article
- Clostridioides difficile infection in nucleic acid amplification test-positive/toxin-negative patients: to treat or not to treat.The Korean journal of internal medicine · 2026Article
- Implementation of two-stage testing forAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Cycle thresholds and discordant 2-step testing for Clostridioides Difficile: Comparison of clinical characteristics and outcomes among discordant and true positive results.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2026Article
- Clinical Outcome of Inflammatory Bowel Disease with Clostridioides difficile Polymerase Chain Reaction Toxin-Positive/Enzyme Immunoassay Toxin-Negative: A Retrospective Cohort Study.Digestive diseases and sciences · 2025Article
- Impact of a multi-step testing algorithm on hospital-onsetAntimicrobial stewardship & healthcare epidemiology : ASHE · 2025Article
- Diagnosis ofJournal of medical microbiology · 2024Review
- Comparative evaluation of the STANDARD M10 and XpertJournal of clinical microbiology · 2024Article
- Potential underreporting of treated patients using aInfection control and hospital epidemiology · 2024Observational
- Clinical outcomes and treatment necessity in patients with toxin-negative Clostridioides difficile stool samples.Annals of clinical microbiology and antimicrobials · 2024Article
- Multicenter evaluation of BioCode GPP for syndromic molecular detection of gastrointestinal pathogens from stool specimens.Journal of clinical microbiology · 2024Article
- Leveraging diagnostic stewardship within antimicrobial stewardship programmes.Drugs in context · 2023Review
- Optimizing the interpretation ofAntimicrobial stewardship & healthcare epidemiology : ASHE · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Clostridioides difficile infection (CDI) is routinely diagnosed by PCR, with or without toxin enzyme immunoassay testing. The role of therapy for positive PCR and negative toxin remains unclear. The objective of this study was to determine whether clinical outcomes of PCR
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.