Evidence map›Paper›PMID 35611617›Full record

ArticleJournal of the Royal Society, Interface2022

Impacts of a delayed and slow-paced vaccination on cases and deaths during the COVID-19 pandemic: a modelling study.

Gustavo Barbosa Libotte, Lucas Dos Anjos, Regina Célia Cerqueira de Almeida, Sandra Mara Cardoso Malta, Roberto de Andrade Medronho

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gustavo Barbosa LibotteNational Laboratory for Scientific Computing, Petrópolis, Rio de Janeiro, 25651-075 Brazil.ORCID 0000-0002-4583-6026
Lucas Dos AnjosNational Laboratory for Scientific Computing, Petrópolis, Rio de Janeiro, 25651-075 Brazil.ORCID 0000-0002-9623-5570
Regina Célia Cerqueira de AlmeidaNational Laboratory for Scientific Computing, Petrópolis, Rio de Janeiro, 25651-075 Brazil.ORCID 0000-0002-9756-8131
Sandra Mara Cardoso MaltaNational Laboratory for Scientific Computing, Petrópolis, Rio de Janeiro, 25651-075 Brazil.ORCID 0000-0003-1272-6039
Roberto de Andrade MedronhoInstitute of Collective Health, School of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-598 Brazil.ORCID 0000-0003-4073-3930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Brazil, vaccination has always cut across party political and ideological lines, which has delayed its start and brought the whole process into disrepute. Such divergences put the immunization of the population in the background and create additional hurdles beyond the pandemic, mistrust and scepticism over vaccines. We conduct a mathematical modelling study to analyse the impacts of late vaccination along with slowly increasing coverage, as well as how harmful it would be if part of the population refused to get vaccinated or missed the second dose. We analyse data from confirmed cases, deaths and vaccination in the state of Rio de Janeiro in the period between 10 March 2020 and 27 October 2021. We estimate that if the start of vaccination had been 30 days earlier, combined with efforts to drive vaccination rates up, about 31 657 deaths could have been avoided. In addition, the slow pace of vaccination and the low demand for the second dose could cause a resurgence of cases as early as 2022. Even when reaching the expected vaccination coverage for the first dose, it is still challenging to increase adherence to the second dose and maintain a high vaccination rate to avoid new outbreaks.

Indexed as

COVID-19VaccinesBrazilHumansPandemicsVaccinationVaccinesavertable deathsCOVID-19delayed start of vaccinationlow vaccination coverageresurgence of cases

Identifiers

PMID35611617
PMCPMC9131126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.