Evidence map›Paper›PMID 35611508›Full record

ArticleInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2023

Comparative cost analysis of liquid embolization systems for brain arteriovenous malformation using a real-world US hospital database: TRUFILL

Sudhakar R Satti, Xiaozhou Fan, Emilie Kottenmeier, Rahul Khanna, Ansaar T Rai

Open access · greenAbstract read
In one paragraph

Article in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sudhakar R SattiDepartment of Neurointerventional Surgery, Christiana Care Health System, Newark, USA.
Xiaozhou FanMedical Device Epidemiology & Real-World Data Sciences, Johnson & Johnson, New Brunswick, NJ, USA.
Emilie KottenmeierHealth Economics and Market Access, Johnson & Johnson, Irvine, CA, USA.
Rahul KhannaMedical Device Epidemiology & Real-World Data Sciences, Johnson & Johnson, New Brunswick, NJ, USA.ORCID 0000-0002-2478-1724
Ansaar T RaiDepartment of Neuroradiology, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA.
Johnson & Johnson (United States) · USChristiana Care Health System · USWest Virginia University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLiquid embolic systems (LES) such as n-butyl cyanoacrylate-based TRUFILL

methodsAdult patients with unruptured bAVMs undergoing endovascular embolization with TRUFILL or Onyx LES between January 1, 2010 and June 30, 2020 were identified from the Premier Healthcare Database. Baseline covariates among the two groups were balanced using propensity score matching. Outcomes including total procedure cost, supply cost, and LOS were examined. A Generalized Estimating Equation model was used to assess outcomes in the matched cohorts.

resultsA total of 1072 patients were included in the study; 140 embolized with TRUFILL (mean age 47.06 [15.72] years, 45.70% male) and 932 embolized with Onyx (mean age 46.80 [16.65] years, 52.30% male). In the post-match cohort, the total procedure costs were lower for the TRUFILL (n = 130) versus Onyx (n = 333) group, though not significantly ($36,798 vs. $40,988; odds ratio [OR] = 0.90, 95% confidence interval [CI]: 0.73-1.10;

conclusionsIn a large, multi-center, real-world sample of patients undergoing bAVM embolization, TRUFILL use was associated with significantly lower supply cost compared to Onyx use.

Indexed as

Embolization, TherapeuticIntracranial Arteriovenous MalformationsAdultBrainDimethyl SulfoxideFemaleHospitalsHumansMaleMiddle AgedPolyvinylsRetrospective StudiesTreatment OutcomeDimethyl SulfoxidePolyvinylsarteriovenous malformationCost analysisonyxtherapeutic embolizationTRUFILL

Identifiers

PMID35611508
PMCPMC10680964
OpenAlexW4281487755

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.