ArticleMicrocirculation (New York, N.Y. : 1994)2022
Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic.
Article in Microcirculation (New York, N.Y. : 1994), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Transplant international : official journal of the European Society for Organ Transplantation · 2024Pooled it
- Preclinical in-vivo cerebrovascular imaging in rodent models: Methods and applications in Alzheimer's disease.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Review
- In Vivo Visualization and Quantification of Dermal Nevus Microvasculature Using Super-Resolution Ultrasound of Erythrocytes.Diagnostics (Basel, Switzerland) · 2026Article
- An Atlas of Neonatal Neurovascular Imaging Anatomy as Depicted with Microvascular Imaging: The Intracranial Arteries.AJNR. American journal of neuroradiology · 2025Review
- An Atlas of Neonatal Neurovascular Imaging Anatomy as Depicted with Microvascular Imaging: The Intracranial Veins.AJNR. American journal of neuroradiology · 2025Review
- Multi-exposure speckle imaging through an optical fiber bundle.Journal of biomedical optics · 2025Article
- Photoacoustic-Strain (PAS) Imaging for Tissue Microcirculation Assessment.IEEE transactions on medical imaging · 2025Article
- Influence of Exposure Time and Driving Frequency on Cytotoxicity in In Vitro Ultrasound With Constant Mechanical Indices.Engineering in life sciences · 2025Article
- Monitoring microvascular changes over time with a repositionable 3D ultrasonic capacitive micromachined row-column sensor.Science advances · 2025Article
- Non-contrast ultrasound assessment of blood flow in clinical practice.Journal of ultrasonography · 2024Article
- Analyses of gingival papilla blood flow via color doppler flow imaging and micro-flow imaging in patients with advanced periodontitis: a clinical pilot study.European journal of medical research · 2024Article
- Ultrasonic-responsive piezoelectric stimulation enhances sonodynamic therapy for HER2-positive breast cancer.Journal of nanobiotechnology · 2024Article
- Ultrasonography of Hepatocellular Carcinoma: From Diagnosis to Prognosis.Journal of clinical and translational hepatology · 2024Review
- Non-contrast ultrasound image analysis for spatial and temporal distribution of blood flow after spinal cord injury.Scientific reports · 2024Article
- FlowMorph: Morphological Segmentation of Ultrasound-Monitored Spinal Cord Microcirculation.IEEE Biomedical Circuits and Systems Conference : healthcare technology : [proceedings]. IEEE Biomedical Circuits and Systems Conference · 2022Article
- Visualizing the Microcirculation.Microcirculation (New York, N.Y. : 1994) · 2022Article
- Ultrasound monitoring of microcirculation: An original study from the laboratory bench to the clinic.Microcirculation (New York, N.Y. : 1994) · 2022Article
- Microvascular assessment of fascio-cutaneous flaps by ultrasound: A large animal study.Frontiers in physiology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveMonitoring microcirculation and visualizing microvasculature are critical for providing diagnosis to medical professionals and guiding clinical interventions. Ultrasound provides a medium for monitoring and visualization; however, there are challenges due to the complex microscale geometry of the vasculature and difficulties associated with quantifying perfusion. Here, we studied established and state-of-the-art ultrasonic modalities (using six probes) to compare their detection of slow flow in small microvasculature.
methodsFive ultrasonic modalities were studied: grayscale, color Doppler, power Doppler, superb microvascular imaging (SMI), and microflow imaging (MFI), using six linear probes across two ultrasound scanners. Image readability was blindly scored by radiologists and quantified for evaluation. Vasculature visualization was investigated both in vitro (resolution and flow characterization) and in vivo (fingertip microvasculature detection).
resultsSuperb Microvascular Imaging (SMI) and Micro Flow Imaging (MFI) modalities provided superior images when compared with conventional ultrasound imaging modalities both in vitro and in vivo. The choice of probe played a significant difference in detectability. The slowest flow detected (in the lab) was 0.1885 ml/s and small microvasculature of the fingertip were visualized.
conclusionsOur data demonstrated that SMI and MFI used with vascular probes operating at higher frequencies provided resolutions acceptable for microvasculature visualization, paving the path for future development of ultrasound devices for microcirculation monitoring.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.