Evidence map›Paper›PMID 35611371›Full record

ArticlePediatric gastroenterology, hepatology & nutrition2022

International Cross-Sectional Survey among Healthcare Professionals on the Management of Cow's Milk Protein Allergy and Lactose Intolerance in Infants and Children.

J Armando Madrazo, Fawaz Alrefaee, Anjan Chakrabarty, Julia C de Leon, Lanlan Geng, Sitang Gong, Ralf G Heine, Anette Järvi, Jarungchit Ngamphaiboon, Christina Ong and 1 more

Open access · diamondAbstract read
In one paragraph

Article in Pediatric gastroenterology, hepatology & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 8 countries.

J Armando MadrazoDepartment of Pediatrics, Universidad Nacional Autónoma de México, México City, México.ORCID https://orcid.org/0000-0001-8499-6535
Fawaz AlrefaeePediatric Department, Al Adan Hospital, Ministry of Health, Kuwait City, Kuwait.ORCID https://orcid.org/0000-0002-7980-1518
Anjan ChakrabartyDepartment of Paediatrics, West Middlesex University Hospital, Isleworth, United Kingdom.ORCID https://orcid.org/0000-0001-7365-3369
Julia C de LeonDepartment of Pediatrics, Cardinal Santos Medical Center, Manila, Philippines.ORCID https://orcid.org/0000-0002-3765-453X
Lanlan GengDepartment of Gastroenterology, Guangzhou Women's and Children's Medical Center, Guangzhou, China.ORCID https://orcid.org/0000-0002-0336-952X
Sitang GongDepartment of Pediatrics, Guangzhou Women's and Children's Medical Center, Guangzhou, China.ORCID https://orcid.org/0000-0002-6899-0616
Ralf G HeineNestlé Health Science, Vevey, Switzerland.ORCID https://orcid.org/0000-0002-3343-0379
Anette JärviNestlé Health Science, Vevey, Switzerland.ORCID https://orcid.org/0000-0001-5757-2091
Jarungchit NgamphaiboonDepartment of Pediatrics, Chualalongkorn University, Bangkok, Thailand.ORCID https://orcid.org/0000-0002-0710-9610
Christina OngDepartment of Paediatric Gastroenterology, KK Women's and Children's Hospital, Singapore.ORCID https://orcid.org/0000-0001-6543-4334
Jossie M RogacionDepartment of Pediatrics, University of the Philippines, Philippine General Hospital, Manila, Philippines.ORCID https://orcid.org/0000-0001-5493-0228
Guangzhou Women and Children Medical Center · CNNestlé (Switzerland) · CHAdan Hospital · KWChulalongkorn University · THKK Women's and Children's Hospital · SGPhilippine General Hospital · PHUniversidad Nacional Autónoma de México · MXWest Middlesex University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The present international survey among healthcare providers aimed to collect data on theoretical knowledge and clinical practices in the diagnosis and management of cow's milk protein allergy (CMPA) and lactose intolerance (LI) in infants. Methods: A global survey was conducted in several countries with diverse health care settings. The survey consisted of multiple-choice questions in 3 main domains: (1) understanding and clinical practices around CMPA and LI; (2) case scenarios; and (3) disease-specific knowledge and potential educational needs. Results: Responses were available from 1,663 participants. About 62% of respondents were general practitioners or general pediatricians, and the remainder were pediatric allergists/gastroenterologists (18%) or other health practitioners (20%). The survey identified knowledge gaps regarding the types of CMPA (IgE-mediated vs. non-IgE-mediated) and the clinical overlap with LI. The survey suggested diverse clinical practices regarding the use of hypoallergenic formulas, as well as misconceptions about the prebiotic benefits of lactose in extensively hydrolyzed formulas in non-breastfed infants with CMPA. Responses to the two case scenarios highlighted varying levels of awareness of the relevant clinical practice guidelines. While respondents generally felt confident in managing infants with CMPA and LI, about 80% expressed an interest for further training in this area. Conclusion: The current survey identified some knowledge gaps and regional differences in the management of infants with CMPA or LI. Local educational activities among general and pediatric healthcare providers may increase the awareness of clinical practice guidelines for the diagnosis and treatment of both conditions and help improve clinical outcomes.

Indexed as

Diet therapyFood hypersensitivityInfant formulaLactaseMedical educationMilk hypersensitivityPractice guideline

Identifiers

PMID35611371
PMCPMC9110852
OpenAlexW4282914944

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.