ArticleWorld journal of clinical cases2022
Echocardiography in the diagnosis of Shone's complex and analysis of the causes for missed diagnosis and misdiagnosis.
Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Clinical presentation and surgical outcomes in patients with Shone's complex: a systematic review.General thoracic and cardiovascular surgery · 2024Pooled it
- Resistant Secondary Hypertension and Severe Pulmonary Hypertension in a Young Adult due to a Rare Cause.Clinical case reports · 2025Article
- Shone᾽s complex in pediatric age group: clinical characteristics, structural components, interventions, and outcomes of a cohort from a single center.BMC pediatrics · 2025Article
- Missed or Delayed Diagnosis of Heart Disease by the General Pediatrician.Children (Basel, Switzerland) · 2025Review
- Shone Complex: A Case Report of Congenital Heart Disease Detected Using Point-of-care Ultrasound.Clinical practice and cases in emergency medicine · 2023Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundShone's complex is a rare syndrome characterized by congenital left heart defects that can differ among the patients.
aimTo use echocardiography in the diagnosis of Shone's complex and analyze the causes of missed diagnosis and misdiagnosis.
methodsThis was a retrospective study of patients who underwent echocardiography and repair surgery from February 14, 2008, to November 22, 2019. The patients were followed once a year at the outpatient clinic after surgery.
resultsSixty-six patients were included. The patients were 2.7 (0.8-5.6) years of age, and 54.5% were male. Ten (15.2%) had a history of heart surgery. The most common heart defect was the Annulo-Leaflet mitral ring (ALMR) (50/66, 75.8%), followed by coarctation of the aorta (CoA) (43/66, 65.2%). The patients had a variety of combinations of defects. Only two (3.0%) patients had all four defects. None of the patients had a family history of congenital heart disease. The preoperative echocardiographic findings were examined against the intraoperative findings. Echocardiography missed an ALMR in 31 patients (47.0%), a parachute mitral valve (PMV) in one patient (1.5%), subaortic stenosis in one patient (1.5%), and CoA in two patients (3.0%).
conclusionEchocardiography is an effective method to diagnose the Shone's complex. Due to this disease's complexity and interindividual variability, Improving the understanding of the disease can reduce misdiagnosis and missed diagnosis.
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