Evidence map›Paper›PMID 35611199›Full record

ArticleWorld journal of clinical cases2022

Washed microbiota transplantation reduces serum uric acid levels in patients with hyperuricaemia.

Jin-Rong Cai, Xin-Wen Chen, Yu-Jian He, Bin Wu, Min Zhang, Li-Hao Wu

Open access · diamondAbstract read
In one paragraph

Article in World journal of clinical cases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. The Gut Microbiome in Hyperuricemia and Gout.Arthritis & rheumatology (Hoboken, N.J.) · 2025
    Review
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jin-Rong CaiSchool of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou 510030, Guangdong Province, China.
Xin-Wen ChenSchool of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou 510030, Guangdong Province, China.
Yu-Jian HeSchool of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou 510030, Guangdong Province, China.
Bin WuSchool of Clinical Medicine, Guangdong Pharmaceutical University, Guangzhou 510030, Guangdong Province, China.
Min ZhangDepartment of Epidemiology and Health Statistics, Guangdong Pharmaceutical University, Guangzhou 510220, Guangdong Province, China.
Li-Hao WuDepartment of Gastroenterology, The First Affiliated Hospital of Guangdong Pharmaceutical University, Guangzhou 510030, Guangdong Province, China.
Guangdong Pharmaceutical University · CNFirst Affiliated Hospital of Guangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies have found that hyperuricaemia (HUA) is closely related to intestinal flora imbalance.

aimThe current study investigated the effects and safety of washed microbiota transplantation (WMT) on serum uric acid (SUA) levels in different populations.

methodsA total of 144 patients who received WMT from July 2016 to April 2020 in the First Affiliated Hospital of Guangdong Pharmaceutical University and had SUA data before treatment were selected. Changes in SUA levels before and after treatment were retrospectively reviewed based on short-term and mid-term effects of WMT regimens. SUA levels measured in the last test within 3 mo after the first WMT represented the short-term effect, and SUA levels measured in the last test within 3-6 mo after the first WMT represented the mid-term effect. The patients were divided into an HUA group (SUA > 416 μM) and a normal uric acid (NUA) group (SUA ≥ 202 μM to ≤ 416 μM) based on pretreatment SUA levels.

resultsAverage short-term SUA levels in the HUA group decreased after WMT (481.00 ± 99.85

conclusionWMT reduces short-term SUA levels in patients with HUA with mild side effects but has no obvious effect on SUA levels in patients with NUA.

Indexed as

EffectHyperuricaemiaIntestinal floraRetrospective studySafetyWashed microbiota transplantation

Identifiers

PMID35611199
PMCPMC9048544
OpenAlexW4226549697

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.