Evidence map›Paper›PMID 35611019›Full record

ArticleCase reports in ophthalmology

Hydrophilic Lens Opacification after Intravitreal Anti-VEGF Injections: A Case Series.

Charbel Wahab, Jad Ayash, Kevin Sayegh, Fady Sammouh, Elias L Warrak

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Charbel WahabDepartment of Ophthalmology, Saint George Hospital, University Medical Center, University of Balamand, Beirut, Lebanon.
Jad AyashDepartment of Ophthalmology, Saint George Hospital, University Medical Center, University of Balamand, Beirut, Lebanon.
Kevin SayeghDepartment of Ophthalmology, Saint George Hospital, University Medical Center, University of Balamand, Beirut, Lebanon.
Fady SammouhDepartment of Ophthalmology, Saint George Hospital, University Medical Center, University of Balamand, Beirut, Lebanon.
Elias L WarrakDepartment of Ophthalmology, Saint George Hospital, University Medical Center, University of Balamand, Beirut, Lebanon.
University of Balamand · LB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objective in this retrospective case series was to report 4 cases of hydrophilic intraocular lens (IOL) opacifications after repeated intravitreal bevacizumab injections. This is a retrospective analysis of all the cases of IOL opacifications presenting to a tertiary referral ophthalmic center in Beirut between January 2013 and January 2019. Four cases were included in the study, of which one was treated for vitreal hemorrhage, the other for macular edema secondary to wet age-related macular edema, and the rest for macular edema secondary to diabetic retinopathy. The mean age of the patients was 71 years with a male predominance and a mean of 5 injections. The IOL opacifications appeared approximately 24 months after first bevacizumab injection. The opacification could be explained by multiple theories such as a possible anterior or posterior segment subclinical inflammation secondary to intraocular interventions, interaction between the hydrophilic properties of the IOLs and anti-vascular endothelial growth factor injection's content, impurities transmission during injection, or faulty IOL manufacturing.

Indexed as

Bevacizumab (Avastin)Hydrophilic intraocular lensIntraocular lens opacificationsIntravitreal injection

Identifiers

PMID35611019
PMCPMC9082158
OpenAlexW4220961951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.