Evidence map›Paper›PMID 35610752›Full record

ArticleJournal of biomedical optics2022

Photoacoustic imaging of posterior periodontal pocket using a commercial hockey-stick transducer.

Lei Fu, Chen Ling, Zhicheng Jin, Jessica Luo, Jorge Palma-Chavez, Zhuohong Wu, Jingcheng Zhou, Jiajing Zhou, Brian Donovan, Baiyan Qi and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. [Mechanism underlying carvacrol-induced alveolar bone repair via the phosphatidylinositol 3-kinase pathway in periodontal disease].Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Biomedical optics express · 2024
    Article
  11. Photoacoustic imaging plus X: a review.Journal of biomedical optics · 2024
    Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Lei FuUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Chen LingUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Zhicheng JinUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Jessica LuoUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Jorge Palma-ChavezUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Zhuohong WuUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Jingcheng ZhouUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Jiajing ZhouUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Brian DonovanUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
Baiyan QiUniversity of California San Diego, Materials Science and Engineering Program, La Jolla, California, United States.
Aditya MishraUniversity of California San Diego, Materials Science and Engineering Program, La Jolla, California, United States.
Tengyu HeUniversity of California San Diego, Materials Science and Engineering Program, La Jolla, California, United States.
Jesse V JokerstUniversity of California San Diego, Department of NanoEngineering, La Jolla, California, United States.
University of California, San Diego · US

Funding

A Miniaturized and High-frequency Acoustic Imaging System for Oral Health and Diseases of the Head and NeckR01DE031307 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jesse Vincent Jokerst · 2022 to 2026
$3.1M
VEVO 3100 + LAXR-X Acoustic Imaging SystemS10OD032268 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2022 to 2022
$893k
Vevo LAZR Photoacoustic Imaging SystemS10OD021821 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HALL, DAVID J · 2016 to 2016
$594k
Non-Invasive Detection and Staging of Decubitus and Diabetic UlcersR21AG065776 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2021
$575k
A Miniaturized Tool for Ultrasound Quantification of Periodontal DiseaseR21DE029025 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2019 to 2020
$409k
Molecular Imaging of Gingipain Activity in Advanced PeriodontitisR21DE029917 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JOKERST, JESSE VINCENT · 2020 to 2021
$406k
NIA NIH HHS R21 AG065776NIDCR NIH HHS R01 DE031307NIDCR NIH HHS R21 DE029025NIDCR NIH HHS R21 DE029917NIH HHS S10 OD021821NIH HHS S10 OD032268
6 · The paper itself

Abstract

significancePhotoacoustic imaging has shown advantages over the periodontal probing method in measuring the periodontal probing depth, but the large size of conventional photoacoustic transducers prevents imaging of the more posterior teeth.

aimOur aim is to develop a photoacoustic imaging system to image the more posterior periodontal pocket. APPROACH: We report a clinical "hockey-stick"-style transducer integrated with fibers for periodontal photoacoustic imaging. Cuttlefish ink labeled the periodontal pocket as the photoacoustic contrast agent.

resultsWe characterized the imaging system and then measured the pocket depth of 35 swine teeth. Three raters evaluated the performance of the hockey-stick transducer. The measurements between the Williams probing (gold standard) and the photoacoustic methods were blinded but highly correlated. We showed a bias of ∼0.3  mm for the imaging-based technique versus Williams probing. The minimum inter-reliability was over 0.60 for three different raters of varying experience, suggesting that this approach to measure the periodontal pocket is reproducible. Finally, we imaged three pre-molars of a human subject. We could access more upper and posterior teeth than conventional linear transducers.

conclusionsThe unique angle shape of the hockey-stick transducer allows it to image more posterior teeth than regular linear transducers. This study demonstrated the ability of a hockey-stick transducer to measure the periodontal pocket via photoacoustic imaging.

Indexed as

HockeyPhotoacoustic TechniquesAnimalsPeriodontal PocketReproducibility of ResultsSwineTransducersclinical attachment lossoptoacousticsoral healthperiodontitisphotoacoustic imaging

Identifiers

PMID35610752
PMCPMC9128833
OpenAlexW4282932317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.