ArticleTrials2022
Effectiveness of a community health worker-delivered care intervention for hypertension control in Uganda: study protocol for a stepped wedge, cluster randomized control trial.
Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05068505 (Effectiveness of a Community Health Worker Delivered Care Intervention for Hypertension Control in Uganda), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effectiveness of a Community Health Worker Delivered Care Intervention for Hypertension Control in Uganda: a Stepped Wedge, Cluster Randomized Control Trial
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Assessing implementation outcomes from studies addressing medication adherence for hypertension management in Sub-Saharan Africa: a systematic review.BMC public health · 2025Pooled it
- Components in downstream health promotions to reduce sugar intake among adults: a systematic review.Nutrition journal · 2024Pooled it
- Hypertension in sub-Saharan Africa: the current profile, recent advances, gaps, and priorities.Journal of human hypertension · 2025Review
- Enhancing Public Knowledge of Risk Factors and Warning Signs for Stroke and Heart Attack Through Home-Based Community Health Worker Interventions: A Cluster Randomized Trial.International journal of general medicine · 2025Article
- Principles for task shifting hypertension and diabetes screening and referral: a qualitative study exploring patient, community health worker and healthcare professional perceptions in rural Uganda.BMC public health · 2023Article
- Challenges to Implementation of Community Health Worker-Led Chronic Obstructive Pulmonary Disease (COPD) Screening and Referral in Rural Uganda: A Qualitative Study using the Implementation Outcomes Framework.International journal of chronic obstructive pulmonary disease · 2023Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
backgroundOver 80% of the morbidity and mortality related to non-communicable diseases (NCDs) occurs in low-income and middle-income countries (LMICs). Community health workers (CHWs) may improve disease control and medication adherence among patients with NCDs in LMICs, particularly in sub-Saharan African settings. In Uganda, and the majority of LMICs, management of uncontrolled hypertension remains limited in constrained health systems. Intervening at the primary care level, using CHWs to improve medical treatment outcomes has not been well studied. We aim to determine the effectiveness of a CHW-led intervention in blood pressure control among confirmed hypertensive patients and patient-related factors associated with uncontrolled hypertension.
methodsWe will conduct a stepped-wedge cluster randomized controlled trial study of 869 adult patients with hypertension attending two NCD clinics to test the effectiveness, acceptability, and fidelity of a CHW-led intervention. The multi-component intervention will be centered on monthly household visits by trained CHWs for a period of 1 year, consisting of the following: (1) blood pressure and sugar monitoring, (2) BMI monitoring, (3) cardiovascular disease risk assessment, (4) using checklists to guide monitoring and referral to clinics, and (5) healthy lifestyle counseling and education. During home visits, CHWs will remind patients of follow-up visits. We will measure blood pressure at baseline and 3-monthly for the entire cohort. We will conduct individual-level mixed effects analyses of study data, adjusting for time and clustering by patient and community.
conclusionThe results of this study will inform community delivered HTN management across a range of LMIC settings.
trial registrationClinicalTrials.gov NCT05068505 . Registered on October 6, 2021.
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