ArticleBMC public health2022
EORTC QLQ-C30 general population normative data for Italy by sex, age and health condition: an analysis of 1,036 individuals.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
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- Pre-treatment cognitive impairment in patients with NSCLC: Prevalence and psychosocial factors.IBRO neuroscience reports · 2026Article
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- "Surviving is not enough": shifting the focus from treatment success to quality of life in anal cancer survivors. Patient- reported outcomes and the evolving landscape of survivorship care.Frontiers in oncology · 2026Article
- Health-Related Quality of Life and Symptom Burden in Patients with Diffuse Large B-Cell Lymphoma Before Treatment with Tafasitamab and Lenalidomide: An Ad Hoc Analysis of Italian Real-World Data from the PRO-MIND Study.Diseases (Basel, Switzerland) · 2025Article
- Health-related quality of life and symptom profile of patients withHemaSphere · 2025Article
- Minimal clinically important difference of EQ-5D-5L, SF-6Dv2, and QLU-C10D in hematologic malignancy patients in China.Health and quality of life outcomes · 2025Article
- The current use and application of thresholds for clinical importance of the EORTC QLQ-C30, the EORTC CAT core and the EORTC QLQ-C15-PAL- a systematic scoping review.Health and quality of life outcomes · 2025Article
- Cancer-Specificity of Sex Differences and Sex-Specific Impact of Sociodemographic Characteristics in Cancer Patients' Health-Related Quality of Life: A Cross-Sectional Study.Psycho-oncology · 2025Article
- Translation and Validation of the Gothenburg Trismus Questionnaire-2 into Italian Language.Journal of clinical medicine · 2025Article
- Surgery Versus Chemoradiation Therapy for Oropharyngeal Squamous Cell Carcinoma: A Multidimensional Cross-Sectional Study.Diseases (Basel, Switzerland) · 2025Article
- Sexual health in female and male cancer survivors - compared with age-matched cancer-free controls in Norway.Acta oncologica (Stockholm, Sweden) · 2025Article
- Neuropsychological and psychosocial assessment of small and non-small lung cancer patients: a study protocol.Frontiers in psychology · 2025Article
- Psychometric performance of EQ-5D-5L and SF-6Dv2 in patients with lymphoma in China.The European journal of health economics : HEPAC : health economics in prevention and care · 2024Article
- Sleep Quality in Head and Neck Cancer.Current oncology (Toronto, Ont.) · 2024Observational
- Robotic natural orifice specimen extraction surgery versus robotic transabdominal specimen extraction surgery for early-stage rectal cancer: a multicenter propensity score-matched analysis (in China).Surgical endoscopy · 2024Article
- General population normative values for the EORTC QLQ-C30 by age, sex, and health condition for the French general population.Journal of patient-reported outcomes · 2024Article
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- Efficacy of natural duct specimen extraction versus conventional laparoscopic surgery for rectal cancer: a single-centre retrospective analysis.American journal of cancer research · 2024Article
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9 authors.
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Abstract
backgroundGeneral population normative values for the widely used health-related quality of life (HRQoL) measure, European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire - Core 30 (EORTC QLQ-C30), are available for a range of countries. These are mostly countries in northern Europe. However, there is still a lack of such normative values for southern Europe. Therefore, this study aims to provide sex-, age- and health condition-specific normative values for the general Italian population for the EORTC QLQ-C30. MATERIAL AND
methodsThis study is based on Italian EORTC QLQ-C30 general population data previously collected in an international EORTC project comprising over 15,000 respondents across 15 countries. Recruitment and assessment were carried out via online panels. Quota sampling was used for sex and age groups (18-39, 40-49, 50-59, 60-69 and ≥ 70 years), separately for each country. We applied weights to match the age and sex distribution in our sample with UN statistics for Italy. Along with descriptive statistics, linear regression models were estimated to describe the associations of sex, age and health condition with the EORTC QLQ-C30 scores.
resultsA total of 1,036 respondents from Italy were included in our analyses. The weighted mean age was 49.3 years, and 536 (51.7%) participants were female. Having at least one health condition was reported by 60.7% of the participants. Men reported better scores than women on all EORTC QLQ-C30 scales but diarrhoea. While the impact of age differed across scales, older age was overall associated with better HRQoL as shown by the summary score. For all scales, differences were in favour of participants who did not report any health condition, compared to those who reported at least one.
conclusionThe Italian normative values for the EORTC QLQ-C30 scales support the interpretation of HRQoL profiles in Italian cancer populations. The strong impact of health conditions on EORTC QLQ-C30 scores highlights the importance of adjusting for the impact of comorbidities in cancer patients when interpreting HRQoL data.
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