Evidence map›Paper›PMID 35610427›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Electrophysiology of the Suprachiasmatic Nucleus: Single-Unit Recording.

Martha U Gillette, Jennifer W Mitchell

Abstract read
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In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Martha U GilletteDepartment of Cell and Developmental Biology and Neuroscience Program, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA. mgillett@illinois.edu.
Jennifer W MitchellDepartment of Cell and Developmental Biology and Neuroscience Program, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL, USA.
University of Illinois Urbana-Champaign · US

Funding

Dynamic Circadian Regulation of the Blood-Brain Interface in a Human Brain-mimicking Microfluid ChipR61HL159948 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GILLETTE, MARTHA U, HAN, BUMSOO · 2021 to 2022
$1.7M
Susceptibility to depression by human disease-causing mutationR21MH110727 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HUNTLEY, GEORGE W. · 2017 to 2018
$466k
High Resolution Analysis of Redox Regulation in DendritesR21MH117377 · NIMH · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI GILLETTE, MARTHA U · 2019 to 2020
$436k
NHLBI NIH HHS R61 HL159948NIMH NIH HHS R21 MH110727NIMH NIH HHS R21 MH117377
6 · The paper itself

Abstract

Oscillatory output from the suprachiasmatic nuclei (SCN) of the hypothalamus communicates time-of-day information to the brain and body. The SCN's intrinsic ~24-h rhythm can be measured in the neuronal firing rate both in vivo and in vitro, where it continues unperturbed. This robust reporter of endogenous physiology in the SCN brain slice can be widely used to study dynamic changes in SCN physiology, its changing sensitivity to phase-altering signals, and underlying mechanisms. To provide relevant and reproducible data, care must be taken to ensure health of the SCN brain slice. The methods detailed here have been proven to produce healthy, long-lived brain slices.

Indexed as

Circadian RhythmSuprachiasmatic NucleusHypothalamusNeuronsCircadian rhythmElectrophysiologyOscillatorPhaseSingle unitSuprachiasmatic nucleus

Identifiers

PMID35610427
OpenAlexW4285078855

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.