Evidence map›Paper›PMID 35610368›Full record

ArticleBritish journal of cancer2022

Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium.

Georgia Martimianaki, Gianfranco Alicandro, Claudio Pelucchi, Rossella Bonzi, Matteo Rota, Jinfu Hu, Kenneth C Johnson, Charles S Rabkin, Linda M Liao, Rashmi Sinha and 32 more

Open access · bronzeAbstract read
In one paragraph

Article in British journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Functions and Clinical Applications of Exosomes in Gastric Cancer.International journal of biological sciences · 2025
    Review
  5. The global gastric cancer consortium: an update from the Stomach cancer Pooling (StoP) project.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors at 20 institutions in 11 countries.

Georgia MartimianakiDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy. georgia.martimianaki@unimi.it.ORCID http://orcid.org/0000-0003-2722-9094
Gianfranco AlicandroDepartment of Pathophysiology and Transplantation, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-0430-2714
Claudio PelucchiDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy.
Rossella BonziDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy.
Matteo RotaDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Jinfu HuHarbin Medical University, Harbin, China.
Kenneth C JohnsonSchool of Epidemiology and Public Health, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Charles S RabkinDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Linda M LiaoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Rashmi SinhaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Zuo-Feng ZhangDepartment of Epidemiology, UCLA Fielding School of Public Health and Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA.
Michela DalmartelloDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0001-8764-9299
Nuno LunetEPIUnit-Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
Samantha MoraisEPIUnit-Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
Domenico PalliCancer Risk Factors and Life-Style Epidemiology Unit, Institute for Cancer Research, Prevention and Clinical Network, ISPRO, Florence, Italy.ORCID http://orcid.org/0000-0002-5558-2437
Monica FerraroniDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy.
Guo-Pei YuMedical Informatics Center, Peking University, Peking, China.
Shoichiro TsuganeEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.ORCID http://orcid.org/0000-0003-4105-2774
Akihisa HidakaEpidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Maria Paula CuradoCentro Internacional de Pesquisas, A.C. Camargo Cancer Center, São Paulo, Brazil.
Emmanuel Dias-NetoCentro Internacional de Pesquisas, A.C. Camargo Cancer Center, São Paulo, Brazil.
David ZaridzeDepartment of clinical epidemiology, N.N. Blokhin National Medical Research Center for Oncology, Moscow, Russia.
Dmitry MaximovitchDepartment of clinical epidemiology, N.N. Blokhin National Medical Research Center for Oncology, Moscow, Russia.
Jesus VioqueConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.ORCID http://orcid.org/0000-0002-2284-148X
Manoli Garcia de la HeraConsortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Lizbeth López-CarrilloMexico National Institute of Public Health, Morelos, Mexico.
Raúl Ulises Hernández-RamírezDepartment of Biostatistics, Yale School of Public Health, Yale School of Medicine, New Haven, CT, USA.
Gerson Shigueaki HamadaNikkei Disease Prevention Center, São Paulo, Brazil.
Mary H WardDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Lina MuDepartment of Epidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY, USA.ORCID http://orcid.org/0000-0003-4799-7517
Reza MalekzadehDigestive Oncology Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farhad PourfarziDigestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran.
Antonia TrichopoulouHellenic Health Foundation, Athens, Greece.
Anna KarakatsaniHellenic Health Foundation, Athens, Greece.
Robert C KurtzDepartment of Medicine, Memorial Sloan Kettering Cancer Centre, New York, NY, USA.
Areti LagiouDepartment of Public and Community Health, School of Public Health, University of West Attica, Athens, Greece.
Pagona LagiouDepartment of Hygiene, Epidemiology and Medical Statistics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Stefania BocciaSection of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
Paolo BoffettaStony Brook Cancer Center, Stony Brook University, Stony Brook, NY, USA.
M Constanza CamargoDivision of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Eva NegriDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy.
Carlo La VecchiaDepartment of Clinical Sciences and Community Health, Branch of Medical Statistics, Biometry and Epidemiology "G.A. Maccacaro", University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0003-1441-897X
University of Milan · ITNational Institutes of Health · USAC Camargo Hospital · BRUniversidade do Porto · PTUniversitat de Miguel Hernández d'Elx · ESArdabil University of Medical Sciences · IRHarbin Medical University · CNHarvard University · USHellenic Health Foundation · GRMemorial Sloan Kettering Cancer Center · USNational and Kapodistrian University of Athens · GRNational Institute of Infectious Diseases · JPPeking University · CNPiedmont Reference Center for Epidemiology and Cancer Prevention · ITStony Brook University · USTehran University of Medical Sciences · IRUCLA Health · USUniversità Cattolica del Sacro Cuore · ITUniversity at Buffalo, State University of New York · USUniversity of Brescia · IT

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundEvidence from epidemiological studies on the role of tea drinking in gastric cancer risk remains inconsistent. We aimed to investigate and quantify the relationship between tea consumption and gastric cancer in the Stomach cancer Pooling (StoP) Project consortium.

methodsA total of 9438 cases and 20,451 controls from 22 studies worldwide were included. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of gastric cancer for regular versus non-regular tea drinkers were estimated by one and two-stage modelling analyses, including terms for sex, age and the main recognised risk factors for gastric cancer.

resultsCompared to non-regular drinkers, the estimated adjusted pooled OR for regular tea drinkers was 0.91 (95% CI: 0.85-0.97). When the amount of tea consumed was considered, the OR for consumption of 1-2 cups/day was 1.01 (95% CI: 0.94-1.09) and for >3 cups/day was 0.91 (95% CI: 0.80-1.03). Stronger inverse associations emerged among regular drinkers in China and Japan (OR: 0.67, 95% CI: 0.49-0.91) where green tea is consumed, in subjects with H. pylori infection (OR: 0.68, 95% CI: 0.58-0.80), and for gastric cardia cancer (OR: 0.64, 95% CI: 0.49-0.84).

conclusionOur results indicate a weak inverse association between tea consumption and gastric cancer.

Indexed as

Helicobacter InfectionsStomach NeoplasmsCase-Control StudiesHumansOdds RatioRisk FactorsTeaTea

Identifiers

PMID35610368
PMCPMC9381730
OpenAlexW4281391945

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.