Evidence map›Paper›PMID 35610279›Full record

ArticleScientific reports2022

Dominant predictors of early post-transplant outcomes based on the Korean Organ Transplantation Registry (KOTRY).

Jong Cheol Jeong, Tai Yeon Koo, Han Ro, Dong Ryeol Lee, Dong Won Lee, Jieun Oh, Jayoun Kim, Dong-Wan Chae, Young Hoon Kim, Kyu Ha Huh and 11 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Jong Cheol JeongDepartment of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.
Tai Yeon KooDepartment of Nephrology, Seongnam Citizens Medical Center, Seongnam, Republic of Korea.
Han RoDepartment of Internal Medicine, Gil Medical Center, Gachon University College of Medicine, Inchon, Republic of Korea.
Dong Ryeol LeeDivision of Nephrology, Medicine, Maryknoll Medical Center, Busan, Republic of Korea.
Dong Won LeeDivision of Nephrology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Republic of Korea.
Jieun OhDepartment of Internal Medicine, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.
Jayoun KimMedical Research Collaborating Center, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Dong-Wan ChaeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Young Hoon KimDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Kyu Ha HuhDepartment of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jae Berm ParkDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Yeong Hoon KimDepartment of Internal Medicine, Inje University Busan Paik Hospital, Busan, Republic of Korea.
Seungyeup HanDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Republic of Korea.
Soo Jin Na ChoiDepartment of Surgery, Chonnam National University Medical School, Gwangju, Republic of Korea.
Sik LeeDepartment of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Republic of Korea.
Sang-Il MinDepartment of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jongwon HaDepartment of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
Myoung Soo KimDepartment of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
Curie AhnDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
Jaeseok YangLaboratory of Transplantation Immunology, Division of Nephrology, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Room 336, 3rd Floor, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. jcyjs@yuhs.ac.
KOTRY Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data for Asian kidney transplants are very limited. We investigated the relative importance of prognostic markers in Asian kidney transplants by using Korean Organ Transplantation Registry (KOTRY) cohort. Prediction models were developed by data-driven variable selection approach. The relative importance of the selected predictors was measured by dominance analysis. A total of 4854 kidney transplant donor-recipient pairs were analyzed. Overall patient survival rates were 99.8%, 98.8%, and 91.8% at 1, 3, and 5 years, respectively. Death-censored graft survival rates were 98.4%, 97.0%, and 95.8% at 1, 3, and 5 years. Biopsy-proven acute rejection free survival rates were 90.1%, 87.4%, and 87.03% at 1, 3, and 5 years. The top 3 dominant predictors for recipient mortality within 1 year were recipient cardiovascular disease history, deceased donor, and recipient age. The dominant predictors for death-censored graft loss within 1 year were acute rejection, deceased donor, and desensitization. The dominant predictors to acute rejection within 1 year were donor age, HLA mismatched numbers, and desensitization. We presented clinical characteristics of patients enrolled in KOTRY during the last 5 years and investigated dominant predictors for early post-transplant outcomes, which would be useful for clinical decision-making based on quantitative measures.

Indexed as

Graft SurvivalKidney TransplantationGraft RejectionHumansRegistriesRepublic of KoreaTissue DonorsTreatment Outcome

Identifiers

PMID35610279
PMCPMC9130148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.