Evidence map›Paper›PMID 35610265›Full record

Trial reportScientific reports2022

Evening light environments can be designed to consolidate and increase the duration of REM-sleep.

Daniel Vethe, H J Drews, J Scott, M Engstrøm, H S A Heglum, J Grønli, J P Wisor, T Sand, S Lydersen, K Kjørstad and 4 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
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  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Daniel VetheDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway. daniel.vethe@ntnu.no.
H J DrewsDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
J ScottDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
M EngstrømDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
H S A HeglumDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
J GrønliDepartment of Biological and Medical Psychology, University of Bergen, Bergen, Norway.
J P WisorSleep and Performance Research Center and Department of Translational Medicine and Physiology, Elson S. Floyd College of Medicine, Washington State University, Spokane, WA, USA.
T SandDepartment of Neuromedicine and Movement Science, Norwegian University of Science and Technology, Trondheim, Norway.
S LydersenRegional Centre for Child and Youth Mental Health and Child Welfare, Department of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
K KjørstadDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
P M P FaalandDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
C L VestergaardDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
K LangsrudDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
H KallestadDepartment of Mental Health, Norwegian University of Science and Technology, Trondheim, Norway.
Norwegian University of Science and Technology · NOSt Olav's University Hospital · NONewcastle University · GBUniversity of Bergen · NOWashington State University Spokane · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evening exposure to short-wavelength light has disruptive effects on circadian rhythms and sleep. These effects can be mitigated by blocking short-wavelength (blue) frequencies, which has led to the development of evening blue-depleted light environments (BDLEs). We have previously reported that residing 5 days in an evening BDLE, compared with residing in a normal indoor light environment of similar photopic lux, advances circadian rhythms and increases the duration of rapid eye movement (REM) sleep in a randomized cross-over trial with twelve healthy participants. The current study extends these findings by testing whether residing in the evening BDLE affects the consolidation and microstructure of REM sleep in the same sample. Evening BDLE significantly reduces the fragmentation of REM sleep (p = 0.0003), and REM sleep microarousals in (p = 0.0493) without significantly changing REM density or the latency to first REM sleep episode. Moreover, the increased accumulation of REM sleep is not at the expense of NREM stage 3 sleep. BDLE further has a unique effect on REM sleep fragmentation (p = 0.0479) over and above that of circadian rhythms phase-shift, indicating a non-circadian effect of BDLE. If these effects can be replicated in clinical populations, this may have a therapeutic potential in disorders characterized by fragmented REM sleep.

Indexed as

Sleep, REMSleep, Slow-WaveCircadian RhythmHumansLightSleep

Identifiers

PMID35610265
PMCPMC9130237
OpenAlexW4281389936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.