ReviewJournal of neurology, neurosurgery, and psychiatry2022
Making sense of phantom limb pain.
Review in Journal of neurology, neurosurgery, and psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 3 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- A systematic literature review to explore lived experiences with phantom limb phenomenon following a lower extremity amputation: a qualitative synthesis.Frontiers in rehabilitation sciences · 2025Pooled it
- Cryoneurolysis for phantom limb pain: a systematic review.Pain management · 2024Pooled it
- Effect of mirror therapy in the treatment of phantom limb pain in amputees: A systematic review of randomized placebo-controlled trials does not find any evidence of efficacy.European journal of pain (London, England) · 2023Pooled it
- Spinal cord stimulation: An emerging strategy for chronic pain relief after spinal cord injury.Neural regeneration research · 2026Article
- Occupational Therapy as Integral Partner in Lower Limb Amputation Rehabilitation: A Clinical Commentary.Occupational therapy in health care · 2026Article
- Resting-State Theta and Alpha Oscillations in Amputation and Phantom Limb Pain: A Pre-Registered High-Density EEG Study.Brain topography · 2026Article
- Impact of transradial amputation and brachial plexus injury on vibrotactile sensation capacity of the upper extremity.Journal of neuroengineering and rehabilitation · 2026Article
- Review
- Assessment of pain and functional outcomes after lower limb amputation: a scoping review.BMJ open · 2026Article
- From Amputation to Persistent Pain: A Review of Molecular and Cellular Processes in Phantom Limb Pain.International journal of molecular sciences · 2026Review
- Long-term outcomes of spinal cord stimulation for refractory phantom limb pain.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Sensory Sensitivity Over Time After Lower Limb Amputation and Its Association with Phantom Limb Pain.Journal of pain research · 2026Article
- A national strategy for a canadian limb loss and limb difference registry.Canadian prosthetics & orthotics journal · 2026Article
- The brain's body map does not forget lost limbs.Nature neuroscience · 2025Article
- Disrupted Biotensegrity in the Fiber Cellular Fascial Network and Neuroma Microenvironment: A Conceptual Framework for "Phantom Limb Pain".International journal of molecular sciences · 2025Review
- Phantom Limb Pain Assessment Tools: A Literature Review Exploring Strengths and Limitations.Archives of rehabilitation research and clinical translation · 2025Review
- Amputees but not healthy subjects optimally integrate non-spatially matched visuo-tactile stimuli.iScience · 2025Article
- A Dissociation Between Primary Motor Cortex Reorganization and Correlation with Pain Intensity in Phantom Limb Pain: A Systematic Review of fMRI Studies.International journal of general medicine · 2025Review
- Pain without presence: a narrative review of the pathophysiological landscape of phantom limb pain.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- Motor cortex stimulation for phantom limb pain treatment.Surgical neurology international · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 6 institutions in 7 countries.
Funding
Abstract
Phantom limb pain (PLP) impacts the majority of individuals who undergo limb amputation. The PLP experience is highly heterogenous in its quality, intensity, frequency and severity. This heterogeneity, combined with the low prevalence of amputation in the general population, has made it difficult to accumulate reliable data on PLP. Consequently, we lack consensus on PLP mechanisms, as well as effective treatment options. However, the wealth of new PLP research, over the past decade, provides a unique opportunity to re-evaluate some of the core assumptions underlying what we know about PLP and the rationale behind PLP treatments. The goal of this review is to help generate consensus in the field on how best to research PLP, from phenomenology to treatment. We highlight conceptual and methodological challenges in studying PLP, which have hindered progress on the topic and spawned disagreement in the field, and offer potential solutions to overcome these challenges. Our hope is that a constructive evaluation of the foundational knowledge underlying PLP research practices will enable more informed decisions when testing the efficacy of existing interventions and will guide the development of the next generation of PLP treatments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.