ReviewAnnual review of microbiology2022
Signal Transduction Network Principles Underlying Bacterial Collective Behaviors.
Review in Annual review of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 57 citations in OpenAlex.
- Bacterial-fungal interactions: connections and consequences.Essays in biochemistry · 2026Review
- A metabolite morphogen coordinates multicellular development inScience advances · 2026Article
- Comparative Metabolomics Reveals the Production of Sulfated Metabolites by Human Gut Bacteria.Journal of the American Chemical Society · 2026Article
- Bacterial Sentience Is Determined by the Stochastic, Chaotic, and Deterministic Behavior of Cytoplasmic Particles.Current issues in molecular biology · 2026Review
- Quorum-sensing, microbiome interactions, and emerging artificial intelligence-assisted anti-virulence strategies in Salmonella Typhi: a critical review of translational opportunities and challenges.Archives of microbiology · 2026Review
- Competing Inter-Domain Quorum-Sensing Systems Control Prophage Lysis-Lysogeny Decisions.bioRxiv : the preprint server for biology · 2026Article
- 4-hydroxy-5-methyl-3(2H)-furanone mediates widespread interkingdom communications between fungi and prokaryotes.Genome biology · 2026Article
- Assessing of auto-inducer type-1 (AI-1) molecule N-(3-hydroxybutanoyl)-L-homoserine lactone responsible for quorum sensing mechanisms in marine pathogenic bacterium Vibrio harveyi.Archives of microbiology · 2026Article
- Molecular basis of quorum-sensing signal transduction by CqsS and its inhibition by CqsA the autoinducer synthase.bioRxiv : the preprint server for biology · 2026Article
- EngineeredBiochemistry · 2026Article
- A branching cell-fate decision in biofilm dispersal enables long-term surface persistence.bioRxiv : the preprint server for biology · 2026Article
- Global Proteomic Analysis Reveals the Roles of MicX in Biofilm Formation and Quorum Sensing inFoods (Basel, Switzerland) · 2026Article
- Virulence regulation in the fish pathogenFrontiers in cellular and infection microbiology · 2026Review
- The role of quorum sensing in rhizosphere community regulation during bacterial wilt pathogen invasion.Frontiers in plant science · 2026Article
- DPO production by gut commensals suggests a broader role in bacterial communication and host-microbiome interactions.NPJ biofilms and microbiomes · 2025Article
- eATP sensing by the purinergic receptor PA2072 for allosteric modulation in intracellular c-di-GMP signaling.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Structure-function studies of Vibrio cholerae quorum-sensing receptor CqsR signal recognition.PLoS pathogens · 2025Article
- Biophysical metabolic modeling of complex bacterial colony morphology.Cell systems · 2025Article
- Systematic modulation of bacterial resource allocation by perturbing RNA polymerase availability via synthetic transcriptional switches.Nucleic acids research · 2025Article
- Insights into the Mechanisms of Small Molecule-Induced Agonism and Antagonism of a Quorum Sensing Receptor inJournal of the American Chemical Society · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Bacteria orchestrate collective behaviors and accomplish feats that would be unsuccessful if carried out by a lone bacterium. Processes undertaken by groups of bacteria include bioluminescence, biofilm formation, virulence factor production, and release of public goods that are shared by the community. Collective behaviors are controlled by signal transduction networks that integrate sensory information and transduce the information internally. Here, we discuss network features and mechanisms that, even in the face of dramatically changing environments, drive precise execution of bacterial group behaviors. We focus on representative quorum-sensing and second-messenger cyclic dimeric GMP (c-di-GMP) signal relays. We highlight ligand specificity versus sensitivity, how small-molecule ligands drive discrimination of kin versus nonkin, signal integration mechanisms, single-input sensory systems versus coincidence detectors, and tuning of input-output dynamics via feedback regulation. We summarize how different features of signal transduction systems allow groups of bacteria to successfully interpret and collectively react to dynamically changing environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.