Evidence map›Paper›PMID 35609608›Full record

ArticleCurrent biology : CB2022

MEL-28/ELYS and CENP-C coordinately control outer kinetochore assembly and meiotic chromosome-microtubule interactions.

Neil Hattersley, Aleesa J Schlientz, Bram Prevo, Karen Oegema, Arshad Desai

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Nuclear transport proteins: structure, function, and disease relevance.Signal transduction and targeted therapy · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Neil HattersleyLudwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA.
Aleesa J SchlientzDivision of Biological Sciences & Department of Cellular & Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Bram PrevoLudwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA.
Karen OegemaLudwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA; Division of Biological Sciences & Department of Cellular & Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA.
Arshad DesaiLudwig Institute for Cancer Research, San Diego Branch, La Jolla, CA 92093, USA; Division of Biological Sciences & Department of Cellular & Molecular Medicine, University of California San Diego, La Jolla, CA 92093, USA. Electronic address: abdesai@ucsd.edu.
Ludwig Cancer Research · USUniversity of California, San Diego · US

Funding

Kinetochore Specification and FunctionR01GM074215 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DESAI, ARSHAD · 2005 to 2025
$8.2M
NIGMS NIH HHS R01 GM074215
6 · The paper itself

Abstract

During mitosis and meiosis in the majority of eukaryotes, centromeric chromatin comprised of CENP-A nucleosomes and their reader CENP-C recruits components of the outer kinetochore to build an interface with spindle microtubules.

Indexed as

Caenorhabditis elegans ProteinsKinetochoresAnimalsCaenorhabditis elegansChromatinChromosomal Proteins, Non-HistoneChromosome SegregationDNA-Binding ProteinsMicrotubule-Associated ProteinsMicrotubulesMitosisNuclear Pore Complex ProteinsSpindle ApparatusCaenorhabditis elegans Proteinscentromere protein CChromatinChromosomal Proteins, Non-HistoneDNA-Binding ProteinsKNL-1 protein, C elegansmel-28 protein, C elegansMicrotubule-Associated ProteinsNDC-80 protein, C elegansNuclear Pore Complex ProteinsC. elegansCENPACENPCcentromereELYSkinetochoreKMN networkmeiosisNDC80nuclear poreoocytespindle

Identifiers

PMID35609608
PMCPMC9216241
OpenAlexW4281296515

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.