Evidence map›Paper›PMID 35609543›Full record

ArticleCurrent biology : CB2022

Thermosensation: How a human-infective nematode finds its host.

Tong Pan, Elizabeth A Ronan, X Z Shawn Xu

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Tong PanLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
Elizabeth A RonanLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.
X Z Shawn XuLife Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: shawnxu@umich.edu.

Funding

Sensory Mechanisms and Disorders - Administrative SupplementT32DC000011 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael Thomas Roberts · 1989 to 2026
$9.5M
Neural and genetic mechanisms underlying behavior in C. elegans - Administrative Supplement for Equipment PurchasesR35GM126917 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, SHAWN · 2018 to 2025
$3.3M
Neural and genetic mechanisms underlying mechanosensation in C. elegansR01DC018167 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI YE, BING · 2020 to 2025
$2.3M
Chemosensation and longevity in C. elegansR01AG067753 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, SHAWN · 2020 to 2024
$1.8M
Mechanisms of Nicotine-Induced BehaviorsR01DA022316 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI XU, SHAWN · 2007 to 2011
$1.5M
NIA NIH HHS R01 AG067753NIDA NIH HHS R01 DA022316NIDCD NIH HHS R01 DC018167NIDCD NIH HHS T32 DC000011NIGMS NIH HHS R35 GM126917
6 · The paper itself

Abstract

The parasitic nematode Strongyloides stercoralis locates human hosts via thermal cues through unknown neural mechanisms. A new study finds that the heat-sensing neuron AFD mediates attraction to human body heat. Interestingly, this neuron also mediates thermotaxis in the nematode C. elegans.

Indexed as

NematodaStrongyloides stercoralisTaxis ResponseAnimalsCaenorhabditis elegansHumansNeurons

Identifiers

PMID35609543
PMCPMC9980427

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.