Evidence map›Paper›PMID 35608812›Full record

ArticleNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2022

Outcome of transcatheter aortic valve replacement in patients over 85 years of age versus patients aged 85 and younger.

F S van den Brink, I Wijtsma, H Amrane, T N E Vossenberg, J Haenen, F Porta, A J Van Boven, S H Hofma

Abstract read
In one paragraph

Article in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Transcatheter aortic valve implantation under 75 years of age: only for high surgical risk patients; but for how long?Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024
    Article
  3. Article
  4. Article
  5. Age is no factor in TAVI.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

F S van den BrinkDepartment of Cardiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands. floris.s.van.den.brink@gmail.com.
I WijtsmaDepartment of Cardiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
H AmraneDepartment of Anaesthesiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
T N E VossenbergDepartment of Cardiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
J HaenenDepartment of Cardio-thoracic surgery, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
F PortaDepartment of Anaesthesiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
A J Van BovenDepartment of Cardiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.
S H HofmaDepartment of Cardiology, Medical Centre Leeuwarden (MCL), Leeuwarden, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe Dutch general population is aging rapidly. Many of these patient are fit and eligible for TAVR. However, studies on outcome in older versus younger patients are scant. MATERIAL AND

methodsA single-centre retrospective study comparing patients older and younger than age 85 on outcome.

results190 patients underwent TAVR: 136 were aged 85 or younger (U85), 54 were older than 85 (O85). The U85 group had more men (U85: 71 [52.2%] vs O85: 19 [35.2%]; p = 0.034), a higher incidence of diabetes (U85: 36 [26.5%] vs O85: 3 [5.6%]; p = 0.001) and atrial fibrillation (U85: 35 [25.7%] vs O85: 5 [9.3%]; p = 0.03) and a higher body mass index (U85: 27.5 [± 5.24] vs O85: 26 [± 3.78]; p = 0.027). In the O85 group there was a lower estimated glomerular filtration rate (O85: 50.28 [± 15.32] ml/min vs U85: 65.25 [± 29.97] ml/min; p = 0.012). There was no difference in 30-day mortality (U85: 6 [4.4%] vs O85: 3 [5.6%]) and 1‑year mortality (U85 9 [6.6%] vs O85 3 [5.6%]) (p = 0.521). There was an equal amount of new onset permanent left bundle branch block (U85: 38 [27.9%] vs O85: 14 [25.9%]; p = 0.896) and permanent pacemaker implantation (U85: 28 [20.6%] vs O85: 28 [20.6%]; p = 0.748). There was no difference in bleeding events (p = 0.469), vascular complications (p = 0.195) or moderate/severe regurgitation (p = 0.972). The U85 group had a slightly longer admission duration (U85 6.29 [± 5.289] days vs O85 5.98 [± 3.328] days (p = 0.037)).

conclusionTAVR in patients over 85 years of age has excellent outcome, comparable to those aged 85 and younger.

Indexed as

OctogenariansOutcomeTranscatheter aortic valve replacement

Identifiers

PMID35608812
PMCPMC9474752

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.