Evidence map›Paper›PMID 35608684›Full record

ArticleClinical oral investigations2022

Artificial intelligence-based diagnostics of molar-incisor-hypomineralization (MIH) on intraoral photographs.

Jule Schönewolf, Ole Meyer, Paula Engels, Anne Schlickenrieder, Reinhard Hickel, Volker Gruhn, Marc Hesenius, Jan Kühnisch

Abstract read
In one paragraph

Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Which diagnostic tools and criteria to use for diagnosis of HSPM and MIH? A systematic review.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026
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  10. Early detection of MIH in children by using artificial intelligence.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jule SchönewolfDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University Munich, Goethestraße 70, 80336, Munich, Germany.
Ole MeyerInstitute for Software Engineering, University of Duisburg-Essen, Essen, Germany.
Paula EngelsDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University Munich, Goethestraße 70, 80336, Munich, Germany.
Anne SchlickenriederDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University Munich, Goethestraße 70, 80336, Munich, Germany.
Reinhard HickelDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University Munich, Goethestraße 70, 80336, Munich, Germany.
Volker GruhnInstitute for Software Engineering, University of Duisburg-Essen, Essen, Germany.
Marc HeseniusInstitute for Software Engineering, University of Duisburg-Essen, Essen, Germany.
Jan KühnischDepartment of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilians University Munich, Goethestraße 70, 80336, Munich, Germany. jkuehn@dent.med.uni-muenchen.de.ORCID http://orcid.org/0000-0003-4063-2291

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to develop and validate a deep learning-based convolutional neural network (CNN) for the automated detection and categorization of teeth affected by molar-incisor-hypomineralization (MIH) on intraoral photographs. MATERIALS AND

methodsThe data set consisted of 3241 intraoral images (767 teeth with no MIH/no intervention, 76 with no MIH/atypical restoration, 742 with no MIH/sealant, 815 with demarcated opacity/no intervention, 158 with demarcated opacity/atypical restoration, 181 with demarcated opacity/sealant, 290 with enamel breakdown/no intervention, 169 with enamel breakdown/atypical restoration, and 43 with enamel breakdown/sealant). These images were divided into a training (N = 2596) and a test sample (N = 649). All images were evaluated by an expert group, and each diagnosis served as a reference standard for cyclic training and evaluation of the CNN (ResNeXt-101-32 × 8d). Statistical analysis included the calculation of contingency tables, areas under the receiver operating characteristic curve (AUCs) and saliency maps.

resultsThe developed CNN was able to categorize teeth with MIH correctly with an overall diagnostic accuracy of 95.2%. The overall SE and SP amounted to 78.6% and 97.3%, respectively, which indicate that the CNN performed better in healthy teeth compared to those with MIH. The AUC values ranging from 0.873 (enamel breakdown/sealant) to 0.994 (atypical restoration/no MIH).

conclusionIt was possible to categorize the majority of clinical photographs automatically by using a trained deep learning-based CNN with an acceptably high diagnostic accuracy. CLINICAL RELEVANCE: Artificial intelligence-based dental diagnostics may support dental diagnostics in the future regardless of the need to improve accuracy.

Indexed as

Dental Enamel HypoplasiaIncisorArtificial IntelligenceDental MaterialsHumansMolarPrevalenceDental MaterialsAutomated image analysisChalky teethConvolutional neural networksDeep learningTransfer learning

Identifiers

PMID35608684
PMCPMC9474479

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.