Evidence map›Paper›PMID 35608680›Full record

ArticleArchives of microbiology2022

Lectins ConA and ConM extracted from Canavalia ensiformis (L.) DC and Canavalia rosea (Sw.) DC inhibit planktonic Candida albicans and Candida tropicalis.

Victor Juno Alencar Fonseca, Ana Lays Braga, Ray Silva de Almeida, Taís Gusmão da Silva, Josefa Carolaine Pereira da Silva, Luciene Ferreira de Lima, Maria Helena Cruz Dos Santos, Romério Rodrigues Dos Santos Silva, Claudener Souza Teixeira, Henrique Douglas Melo Coutinho and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Archives of microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 27 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Victor Juno Alencar FonsecaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Ana Lays BragaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Ray Silva de AlmeidaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Taís Gusmão da SilvaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Josefa Carolaine Pereira da SilvaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Luciene Ferreira de LimaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Maria Helena Cruz Dos SantosCentro de Ciências Agrárias e da Biodiversidade, Universidade Federal Do Cariri, Crato, CE, Brazil.
Romério Rodrigues Dos Santos SilvaCentro de Ciências Agrárias e da Biodiversidade, Universidade Federal Do Cariri, Crato, CE, Brazil.
Claudener Souza TeixeiraCentro de Ciências Agrárias e da Biodiversidade, Universidade Federal Do Cariri, Crato, CE, Brazil.
Henrique Douglas Melo CoutinhoUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil. hdmcoutinho@urca.br.ORCID http://orcid.org/0000-0002-6634-4207
Maria Flaviana Bezerra Morais-BragaUniversidade Regional do Cariri, URCA, Cel Antônio Luis, Pimenta, Crato, CE, 1161, 63105-000, Brazil.
Universidade Regional do Cariri · BRUniversidade Federal do Cariri · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lectins participate in the defense against microorganisms and in signaling the damage caused by pathogens to the cell surface and/or intracellular in plants. This study aims to analyze the antifungal potential of lectins extracted from seeds of Canavalia ensiformis (L.) DC and Canavalia rosea (Sw.) DC, against Candida albicans and Candida tropicalis. The antimicrobial tests were performed by microdilution against Candida spp. The test to verify the combined lectin/fluconazole effect was performed using subinhibitory concentrations of lectins and with antifungal ranging from 0.5 to 512 µg/mL. The ability to inhibit the morphological transition of Candida spp. was evaluated by microcultivation in a moist chamber. The results of the minimum inhibitory concentration revealed no antifungal activity against the tested strains. However, lectins modified the action of fluconazole, reducing the IC

Indexed as

Candida albicansCandida tropicalisAntifungal AgentsCanavaliaCandidaConcanavalin AFluconazoleLectinsMicrobial Sensitivity TestsPlanktonAntifungal AgentsConcanavalin AFluconazoleLectinsAntifungalOpportunistic pathogensPlant proteins

Identifiers

PMID35608680
PMCPMC9127036
OpenAlexW4282920557

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.