Evidence map›Paper›PMID 35608676›Full record

ArticleInternational orthopaedics2022

Association between pre-operative complications, comorbidities, and in-hospital mortality in a hip fracture cohort: a register study in a tertiary hospital in Brazil.

Andre Moreira Fogaça de Souza, Abner Macola, David Nicoletti Gumieiro, Gustavo Augusto Nicolodi, Rodrigo Moreira E Lima, Marcos Ferreira Minicucci, Paula Schmidt Azevedo, Opinder Sahota, Lais Helena Navarro E Lima

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In one paragraph

Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Andre Moreira Fogaça de SouzaAnesthesiology Department, Botucatu Medical School, São Paulo State University, Botucatu, Brazil.
Abner MacolaAnesthesiology Department, Botucatu Medical School, São Paulo State University, Botucatu, Brazil.
David Nicoletti GumieiroSurgery and Orthopedic Department, Botucatu Medical School, São Paulo State University, UNESP, Botucatu, Brazil.
Gustavo Augusto NicolodiAnesthesiology Department, Botucatu Medical School, São Paulo State University, Botucatu, Brazil.
Rodrigo Moreira E LimaAnesthesiology Department, Queen's University, Kingston, Canada.
Marcos Ferreira MinicucciInternal Medicine Department, Botucatu Medical School, São Paulo State University, UNESP, Rubiao Junior s/n, Botucatu, SP, CEP, 18618-970, Brazil. marcos.minicucci@unesp.br.
Paula Schmidt AzevedoInternal Medicine Department, Botucatu Medical School, São Paulo State University, UNESP, Rubiao Junior s/n, Botucatu, SP, CEP, 18618-970, Brazil.
Opinder SahotaOrthogeriatric Medicine, University of Nottingham, Nottingham, UK.
Lais Helena Navarro E LimaAnesthesiology Department, Botucatu Medical School, São Paulo State University, Botucatu, Brazil.
Universidade Estadual Paulista (Unesp) · BRQueen's University · CAUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe incidence of hip fractures is increasing exponentially due to an aging Brazilian population. Older people had significant comorbidities which increases the risk of post-operative mortality. Our purpose was to examine the association between pre-operative infections and comorbidities on the risk of post-operative in-hospital mortality after proximal femur fracture surgery's, beyond that, to evaluate the association between comorbidities and time to surgery.

methodsThis is a population-based cohort retrospective study, using medical records of all six year consecutive surgical procedures for correction of hip fracture in a tertiary teaching Hospital in Brazil. The exclusion criteria aimed to exclusively allocate patients who had their first hip fracture secondary to low-energy trauma. Multivariate logistical regression was performed and receiver operating characteristic (ROC) curve with area under curve (AUC) to evaluate the sensitivity and specificity of the model. p-value < 0.05 was considered significant.

resultsFinal sample was composed by 856 consecutive patients with 81 years of median and 164 patients were excluded. The median length of hospital say was five days with - l mortality at 3.6%. Significant variables for increased mortality included the presence of pre-operative infection (odds ratio (OR): 3.9(1.12-8.54), chronic obstructive pulmonary disease (COPD) (OR: 3.83(1.36-10.82)), and systemic arterial hypertension (SAH) (OR: 4.1(1.18-14.25)). Development of pre-operative infection was associated with a delay to surgery (OR: 1.1 (1.08-1.13)).

conclusionsIn older people with proximal femur fracture, the presence of pre-operative infection, COPD and SAH were the strongest risk factor for post-operative in-hospital mortality. Pre-operative infection was associated with statistically significant delay to surgery.

Indexed as

Hip FracturesPulmonary Disease, Chronic ObstructiveAgedBrazilHospital MortalityHumansPostoperative ComplicationsRetrospective StudiesRisk FactorsTertiary Care CentersChronic obstructive pulmonary diseaseComorbiditiesHip fractureRisk factorsSystemic arterial hypertension

Identifiers

PMID35608676
OpenAlexW4282941862

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.