Evidence map›Paper›PMID 35608612›Full record

ArticleEmerging infectious diseases2022

Economic Burden of Reported Lyme Disease in High-Incidence Areas, United States, 2014-2016.

Sarah A Hook, Seonghye Jeon, Sara A Niesobecki, AmberJean P Hansen, James I Meek, Jenna K H Bjork, Franny M Dorr, Heather J Rutz, Katherine A Feldman, Jennifer L White and 4 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

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  11. Lyme Disease and Health Care Costs.JAMA network open · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sarah A Hook
Seonghye Jeon
Sara A Niesobecki
AmberJean P Hansen
James I Meek
Jenna K H Bjork
Franny M Dorr
Heather J Rutz
Katherine A Feldman
Jennifer L White
P Bryon Backenson
Manjunath B Shankar
Martin I Meltzer
Alison F Hinckley

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approximately 476,000 cases of Lyme disease are diagnosed in the United States annually, yet comprehensive economic evaluations are lacking. In a prospective study among reported cases in Lyme disease-endemic states, we estimated the total patient cost and total societal cost of the disease. In addition, we evaluated disease and demographic factors associated with total societal cost. Participants had a mean patient cost of ≈$1,200 (median $240) and a mean societal cost of ≈$2,000 (median $700). Patients with confirmed disseminated disease or probable disease had approximately double the societal cost of those with confirmed localized disease. The annual, aggregate cost of diagnosed Lyme disease could be $345-968 million (2016 US dollars) to US society. Our findings emphasize the importance of effective prevention and early diagnosis to reduce illness and associated costs. These results can be used in cost-effectiveness analyses of current and future prevention methods, such as a vaccine.

Indexed as

Borrelia burgdorferiIxodesLyme DiseaseAnimalsFinancial StressHumansIncidenceProspective StudiesUnited StatesbacteriaBorrelia burgdorferiConnecticutcost of illnesscurrent procedural terminologyIxodes pacificusIxodes scapularisLyme diseaseMarylandMinnesotaNew Yorksocietal costticksUnited Statesvector-borne diseases

Identifiers

PMID35608612
PMCPMC9155891

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.