ArticleThe Angle orthodontist2022
Influence of genotype and perioral musculature on maxillary and mandibular development.
Article in The Angle orthodontist, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Association between myosin 1H polymorphisms and skeletal-facial profile in Taiwanese patients with mandibular prognathism.Journal of dental sciences · 2026Article
- Detection of Lip, Tongue, Masseter, and Temporalis Muscle Contractions with Electromyography Tools as an Early Diagnostic Medium for Dentoalveolar Malocclusion.European journal of dentistry · 2025Article
- The Association of ACTN3 Rs1815739 Polymorphism with Various Malocclusion Phenotype.Turkish journal of orthodontics · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo determine whether there is an association between skeletal jaw position and perioral musculature, and if genotypes can predict skeletal growth. MATERIALS AND
methodsA prospective study on 42 patients over 1 year was performed. The study included 22 females and 20 males with and average age of 28.5 years. Lip strength was compared to radiographic cephalometric measurements. Allelic and genotypic frequencies from polymorphisms rs678397 and rs1815739 in ACTN3 and rs10850110 in MYO1H were compared to each variable. Chi-square and Fisher exact tests were used to determine if differences were statistically significant (alpha = 0.05).
resultsThe data showed significant differences between rs678397 genotype and allele frequencies and SNA angle (P = .01; P = .003, respectively); between rs1815739 allele frequency and SNA angle (P = .01); between rs678397 allele frequency and ANB angle (P = .049); between rs678397 genotype and allele frequencies and lip strength in females (P = .045; P = .02); and between rs678397 allele frequency and overall lip strength (P = .049), after mean strength values used as cut off being customized by sex.
conclusionsPolymorphisms in ACTN3 are associated with weak lips and larger SNA and ANB angles.
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Registered trials
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