Evidence map›Paper›PMID 35608515›Full record

ArticleGlobal spine journal2024

Bone Mineral Density T-Score is an Independent Predictor of Major Blood Loss in Adult Spinal Deformity Surgery.

Andrew B Harris, Kevin Y Wang, Kevin Mo, Floreana Kebaish, Michael Raad, Varun Puvanesarajah, Farah Musharbash, Brian Neuman, Akhil Jay Khanna, Khaled M Kebaish

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global spine journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Andrew B HarrisDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Kevin Y WangDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Kevin MoDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-7728-0093
Floreana KebaishDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Michael RaadDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Varun PuvanesarajahDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Farah MusharbashDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Brian NeumanDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Akhil Jay KhannaDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.
Khaled M KebaishDepartment of Orthopaedic Surgery, The Johns Hopkins University, Baltimore, MD, USA.ORCID 0000-0002-1235-6202
Johns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective Cohort Study.

objectiveThe purpose of this study was to determine the effect of low bone mineral density (BMD), as assessed by preoperative Dual-energy X-ray Absorptiometry (DEXA) scans, on intraoperative blood loss following adult spinal deformity (ASD) surgery.

methodsPatients who received spinal fusion for ASD (>5 levels fused) at a single academic center from 2010-2018 were included in this study. The lowest preoperative T-score was recorded for patients who had preoperative DEXA scans within a year of surgery. Patients with liver/kidney disease or on prescription anticoagulant medication were excluded. Major blood loss was a binary variable defined as above or below the 90

results91 patients were identified in the cohort. Mean age was 63 ± 11.6 years, 81% female. 56 (62%) of cases included revision of previous instrumentation. Patients had a mean SVA of 9.6 ± 8.6 cm and median of 9 vertebrae fused (range 5-22). The average T-score was -1.2 ± 1.0. Each point lower T-score was associated with significantly higher odds of major blood loss (OR 2.5, 95% CI 1.0 - 5.9) when controlling for age, number of vertebrae fused, 3-column osteotomy, preoperative platelet count and primary vs. revision surgery.

conclusionsPreoperative T-score is independently associated with increased odds of major blood loss in ASD surgery.

Indexed as

adult spinal deformityblood lossbone mineral densitydual-energy x-ray absorptiometr scanosteoporosis

Identifiers

PMID35608515
PMCPMC10676180
OpenAlexW4281394032

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.