Evidence map›Paper›PMID 35608484›Full record

Trial reportAmerican journal of respiratory and critical care medicine2022

The Effect of a Liberal Approach to Glucose Control in Critically Ill Patients with Type 2 Diabetes: A Multicenter, Parallel-Group, Open-Label Randomized Clinical Trial.

Alexis P Poole, Mark E Finnis, James Anstey, Rinaldo Bellomo, Shailesh Bihari, Vishwanath Biradar, Sarah Doherty, Glenn Eastwood, Simon Finfer, Craig J French and 14 more

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in American journal of respiratory and critical care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Diabetes Management Strategies in Intensive Care Settings.The Medical clinics of North America · 2026
    Review
  4. Article
  5. Article
  6. Accuracy of continuous glucose monitoring in critically ill patients.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025
    Article
  7. Review
  8. Critical care nutrition and the legacy of Rinaldo Bellomo.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2025
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Observational
  17. Review
  18. Article
  19. Article
  20. The Optimal Glycemic Control in Patients with Diabetes in the ICU: Where Is the Sweet Spot?American journal of respiratory and critical care medicine · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 14 institutions in 4 countries.

Alexis P PooleDiscipline of Acute Care Medicine and.
Mark E FinnisDiscipline of Acute Care Medicine and.
James AnsteyDepartment of Critical Care, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.
Rinaldo BellomoAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.
Shailesh BihariDepartment of Intensive and Critical Care Unit, Flinders Medical Centre, Bedford Park, South Australia, Australia.ORCID 0000-0001-7553-8620
Vishwanath BiradarDepartment of Intensive Care, Lyell McEwin Hospital, Elizabeth Vale, South Australia, Australia.
Sarah DohertyDepartment of Intensive Care, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Glenn EastwoodAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.
Simon FinferThe George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.
Craig J FrenchDepartment of Critical Care, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.
Simon HellerClinical Diabetes, Endocrinology, and Metabolism, University of Sheffield, Sheffield, United Kingdom.
Michael HorowitzCentre for Research Excellence in Translating Nutrition Science to Good Health, University of Adelaide, Adelaide, South Australia, Australia.
Palash KarDiscipline of Acute Care Medicine and.
Peter S KrugerDepartment of Intensive Care, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia.
Matthew J MaidenDiscipline of Acute Care Medicine and.ORCID 0000-0003-4345-3213
Johan MårtenssonSection of Anaesthesia and Intensive Care, Department of Physiology and Pharmacology, Karolinska Institute, Stockholm, Sweden.
Colin J McArthurDepartment of Critical Care Medicine and.
Shay P McGuinnessCardiothoracic and Vascular Intensive Care and High Dependency Unit, Auckland District Health Board, Auckland, New Zealand.
Paul J SecombeAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.
Antony E TobinDepartment of Critical Care, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.
Andrew A UdyAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.
Paul J YoungAustralian and New Zealand Intensive Care Research Centre, School of Public Health and Preventive Medicine, Monash University, Prahran, Victoria, Australia.ORCID 0000-0002-3428-3083
Adam M DeaneDepartment of Critical Care, Melbourne Medical School, The University of Melbourne, Parkville, Victoria, Australia.ORCID 0000-0002-7620-5577
LUCID Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG)
The University of Melbourne · AUThe Royal Melbourne Hospital · AUAustralian and New Zealand Intensive Care Society · AUAuckland District Health Board · NZBarwon Health · AUFlinders Medical Centre · AUIntensive Care Society · GBKarolinska Institutet · SELyell McEwin Hospital · AURoyal Adelaide Hospital · AUThe Alfred Hospital · AUThe University of Queensland · AUUniversity of Sheffield · GBUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2HypoglycemiaAdultAustraliaBlood GlucoseCritical IllnessHumansHypoglycemic AgentsInsulinBlood GlucoseHypoglycemic AgentsInsulinblood glucosecritical illnessdiabeteshypoglycemiaintensive care

Identifiers

PMID35608484
OpenAlexW4281401333

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.