Evidence map›Paper›PMID 35608037›Full record

ReviewAmerican journal of men's health

Microplastics May Be a Significant Cause of Male Infertility.

Chenming Zhang, Jianshe Chen, Sicheng Ma, Zixue Sun, Zulong Wang

Abstract readReview
In one paragraph

Review in American journal of men's health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  7. Yamabushitake Mushroom (International journal of molecular sciences · 2025
    Article
  8. Review
  9. Detection of microplastics in the human penis.International journal of impotence research · 2025
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chenming ZhangHenan University of Chinese Medicine, Zhengzhou, Henan, China.ORCID 0000-0003-1426-0092
Jianshe ChenHenan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Sicheng MaHenan University of Chinese Medicine, Zhengzhou, Henan, China.
Zixue SunHenan Province Hospital of Traditional Chinese Medicine, Zhengzhou, Henan, China.
Zulong WangThe First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the problematic degradation properties of plastics, the decomposition of plastic results in the formation of numerous microplastics (MPs), less than 5 mm in diameter. These MPs enter the soil and the ocean, eventually passing through the air, water, or food chain back to the human body and harming human health. In the last 80 years, male semen analysis parameters have shown a significant decline for unknown reasons, speculated to be caused by pollutants. No studies examined the relationship between human MP exposure and male infertility. In this article, we reviewed the relevant animal experimental research literature in recent years and calculated that the minimum human equivalent dose of MPs leading to abnormal male semen quality is 0.016 mg/kg/d. The literature comparison found that MP exposure in Japan and South Korea was close to this value. These results suggest that MPs can affect male semen quality and that MPs may significantly impact male fertility.

Indexed as

Infertility, MaleMicroplasticsAnimalsHumansMalePlasticsSemen AnalysisSoilMicroplasticsPlasticsSoilmale infertilitymicroplasticssperm quality

Identifiers

PMID35608037
PMCPMC9134445

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.